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State Street SPDR S&P Biotech ETF

812 hedge funds and large institutions have $16.5B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 230 funds opening new positions, 232 increasing their positions, 204 reducing their positions, and 53 closing their positions.

New
Increased
Maintained
Reduced
Closed

334% more first-time investments, than exits

New positions opened: 230 | Existing positions closed: 53

33% more capital invested

Capital invested by funds: $12.4B → $16.5B (+$4.06B)

24% more funds holding

Funds holding: 655812 (+157)

14% more repeat investments, than reductions

Existing positions increased: 232 | Existing positions reduced: 204

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

15.4% less ownership

Funds ownership: 214.61%199.2% (-15%)

51% less call options, than puts

Call options by funds: $3.12B | Put options by funds: $6.42B

Holders
812
Holders Change
+157
Holders Change %
+23.97%
% of All Funds
9.88%
Holding in Top 10
19
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+5.56%
% of All Funds
0.23%
New
230
Increased
232
Reduced
204
Closed
53
Calls
$3.12B
Puts
$6.42B
Net Calls
-$3.31B
Net Calls Change
-$2.53B
Name Holding Trade Value Shares
Change
Change in
Stake
BO
451
Bank OZK
Arkansas
$484K
ISL
452
Ingalls & Snyder LLC
New York
$484K -$3.44K -30 -0.8%
BCI
453
Blue Capital Inc
Nebraska
$478K +$450K +3,922 New
FA
454
Fortis Advisors
Pennsylvania
$476K -$88.3K -770 -16%
MBT
455
Montecito Bank & Trust
California
$476K
WSC
456
Wellington Shields & Co
New York
$476K
CIA
457
Compass Ion Advisors
Pennsylvania
$474K +$11.1K +97 +3%
AG
458
Ascent Group
Virginia
$473K +$445K +3,883 New
RG
459
Rathbones Group
United Kingdom
$473K +$445K +3,883 New
SFA
460
Sequoia Financial Advisors
Ohio
$468K +$50.9K +444 +13%
CA
461
Continuum Advisory
Idaho
$467K -$16.6K -145 -4%
XT
462
XTX Topco
Cayman Islands
$463K -$515K -4,489 -54%
Bank of New York Mellon
463
Bank of New York Mellon
New York
$460K -$52.2K -455 -11%
AAM
464
Ameraudi Asset Management
New York
$457K
LI
465
LMCG Investments
Massachusetts
$454K
Twin Tree Management
466
Twin Tree Management
Texas
$453K -$76M -662,470 -99%
BFF
467
Byrne Financial Freedom
Massachusetts
$451K +$53K +462 +14%
SI
468
Sava Infond
Slovenia
$451K +$424K +3,700 New
ATC
469
Advantage Trust Company
Kansas
$444K -$68.8K -600 -14%
NCM
470
NCM Capital Management
New Jersey
$441K +$459 +4 +0.1%
Luther King Capital Management (LKCM)
471
Luther King Capital Management (LKCM)
Texas
$439K
BCV
472
Banque Cantonale Vaudoise
Switzerland
$437K +$411K +3,585 New
PCFFS
473
Pacific Center for Financial Services
California
$437K
AWM
474
Axxcess Wealth Management
California
$431K +$405K +3,535 New
KPWS
475
Kestra Private Wealth Services
Texas
$430K -$18.7K -163 -4%