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State Street SPDR S&P Biotech ETF

793 hedge funds and large institutions have $16.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 218 funds opening new positions, 227 increasing their positions, 204 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

16.62% less ownership

Funds ownership: 214.6%197.98% (-17%)

51% less call options, than puts

Call options by funds: $3.1B | Put options by funds: $6.39B

Holders
793
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
19
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$3.1B
Puts
$6.39B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
RG
451
Rathbones Group
United Kingdom
$473K
AG
452
Ascent Group
Virginia
$473K
SFA
453
Sequoia Financial Advisors
Ohio
$468K
CA
454
Continuum Advisory
Idaho
$467K
XT
455
XTX Topco
Cayman Islands
$463K
Bank of New York Mellon
456
Bank of New York Mellon
New York
$460K
AAM
457
Ameraudi Asset Management
New York
$457K
LI
458
LMCG Investments
Massachusetts
$454K
Twin Tree Management
459
Twin Tree Management
Texas
$453K
BFF
460
Byrne Financial Freedom
Massachusetts
$451K
SI
461
Sava Infond
Slovenia
$451K
ATC
462
Advantage Trust Company
Kansas
$444K
Luther King Capital Management (LKCM)
463
Luther King Capital Management (LKCM)
Texas
$439K
BCV
464
Banque Cantonale Vaudoise
Switzerland
$437K
PCFFS
465
Pacific Center for Financial Services
California
$437K
AWM
466
Axxcess Wealth Management
California
$431K
KPWS
467
Kestra Private Wealth Services
Texas
$430K
GC
468
Gruss & Co
Florida
$427K
MC
469
Mathes Company
New York
$423K
MIM
470
Miller Investment Management
Pennsylvania
$419K
IAN
471
Integrated Advisors Network
Texas
$411K
IPAM
472
Investment Partners Asset Management
New Jersey
$399K
CB
473
Commerce Bank
Missouri
$397K
KI
474
KTF Investments
California
$397K
FA
475
Fiduciary Alliance
South Carolina
$389K