XBI icon

State Street SPDR S&P Biotech ETF

809 hedge funds and large institutions have $16.5B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 229 funds opening new positions, 230 increasing their positions, 204 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding

Funds holding:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

15.53% less ownership

Funds ownership: 214.6%199.07% (-16%)

51% less call options, than puts

Call options by funds: $3.12B | Put options by funds: $6.42B

Holders
809
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
19
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$3.12B
Puts
$6.42B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
SIG
426
Sargent Investment Group
Maryland
$569K
FNBT
427
FineMark National Bank & Trust
Florida
$567K
M&T Bank
428
M&T Bank
New York
$561K
SSCA
429
South Shore Capital Advisors
Massachusetts
$549K
AIP
430
Almanack Investment Partners
Pennsylvania
$544K
AWM
431
Avaii Wealth Management
Wisconsin
$541K
CW
432
CreativeOne Wealth
Kansas
$535K
US Bancorp
433
US Bancorp
Minnesota
$534K
BFA
434
Beaumont Financial Advisors
Massachusetts
$528K
DAC
435
Dutch Asset Corp
New York
$527K
PCTC
436
Perkins Coie Trust Company
Washington
$521K
PIA
437
Powell Investment Advisors
Florida
$518K
FDCDDQ
438
Federation des caisses Desjardins du Quebec
Quebec, Canada
$512K
SIC
439
Salem Investment Counselors
North Carolina
$509K
MFIM
440
Mesirow Financial Investment Management
Illinois
$509K
BA
441
Bridgewater Advisors
New York
$507K
ATPW
442
Ashton Thomas Private Wealth
Arizona
$507K
PHS
443
Pekin Hardy Strauss
Illinois
$507K
First Manhattan
444
First Manhattan
New York
$500K
CI
445
CX Institutional
Indiana
$493K
TI
446
Tidal Investments
Wisconsin
$491K
AC
447
Apella Capital
Connecticut
$490K
UCFA
448
United Capital Financial Advisors
Texas
$488K
BO
449
Bank OZK
Arkansas
$484K
ISL
450
Ingalls & Snyder LLC
New York
$484K