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State Street SPDR S&P Biotech ETF

812 hedge funds and large institutions have $16.5B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 230 funds opening new positions, 232 increasing their positions, 204 reducing their positions, and 53 closing their positions.

New
Increased
Maintained
Reduced
Closed

334% more first-time investments, than exits

New positions opened: 230 | Existing positions closed: 53

33% more capital invested

Capital invested by funds: $12.4B → $16.5B (+$4.06B)

24% more funds holding

Funds holding: 655812 (+157)

14% more repeat investments, than reductions

Existing positions increased: 232 | Existing positions reduced: 204

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

15.4% less ownership

Funds ownership: 214.61%199.2% (-15%)

51% less call options, than puts

Call options by funds: $3.12B | Put options by funds: $6.42B

Holders
812
Holders Change
+157
Holders Change %
+23.97%
% of All Funds
9.88%
Holding in Top 10
19
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+5.56%
% of All Funds
0.23%
New
230
Increased
232
Reduced
204
Closed
53
Calls
$3.12B
Puts
$6.42B
Net Calls
-$3.31B
Net Calls Change
-$2.53B
Name Holding Trade Value Shares
Change
Change in
Stake
JCM
426
Jacobi Capital Management
Pennsylvania
$574K +$1.72K +15 +0.3%
FWM
427
FFT Wealth Management
Pennsylvania
$569K -$41.9K -365 -7%
SIG
428
Sargent Investment Group
Maryland
$569K +$535K +4,670 New
FNBT
429
FineMark National Bank & Trust
Florida
$567K
M&T Bank
430
M&T Bank
New York
$561K -$104K -904 -16%
SSCA
431
South Shore Capital Advisors
Massachusetts
$549K +$516K +4,500 New
AIP
432
Almanack Investment Partners
Pennsylvania
$544K +$511K +4,458 New
AWM
433
Avaii Wealth Management
Wisconsin
$541K -$6.76K -59 -1%
CW
434
CreativeOne Wealth
Kansas
$535K +$503K +4,388 New
US Bancorp
435
US Bancorp
Minnesota
$534K -$43.8K -382 -8%
BFA
436
Beaumont Financial Advisors
Massachusetts
$528K +$117K +1,019 +31%
DAC
437
Dutch Asset Corp
New York
$527K +$496K +4,323 New
PCTC
438
Perkins Coie Trust Company
Washington
$521K
PIA
439
Powell Investment Advisors
Florida
$518K
FDCDDQ
440
Federation des caisses Desjardins du Quebec
Quebec, Canada
$512K +$414K +3,608 +606%
SIC
441
Salem Investment Counselors
North Carolina
$509K
MFIM
442
Mesirow Financial Investment Management
Illinois
$509K -$114K -993 -19%
BA
443
Bridgewater Advisors
New York
$507K
ATPW
444
Ashton Thomas Private Wealth
Arizona
$507K
PHS
445
Pekin Hardy Strauss
Illinois
$507K +$53.8K +469 +13%
First Manhattan
446
First Manhattan
New York
$500K -$39K -340 -8%
CI
447
CX Institutional
Indiana
$493K -$936K -8,160 -67%
TI
448
Tidal Investments
Wisconsin
$491K -$557K -4,854 -55%
AC
449
Apella Capital
Connecticut
$490K +$461K +4,020 New
UCFA
450
United Capital Financial Advisors
Texas
$488K +$76.2K +665 +20%