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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
BO
426
Bank OZK
Arkansas
$322K – – –
CCG
427
Coastwise Capital Group
California
$322K +$6.49K +80 +2%
CFG
428
Citizens Financial Group
Rhode Island
$321K +$9K +111 +3%
MBT
429
Montecito Bank & Trust
California
$316K – – –
WSC
430
Wellington Shields & Co
New York
$316K – – –
CG
431
Caprock Group
Idaho
$313K – – –
First Manhattan
432
First Manhattan
New York
$309K – – –
FAIM
433
Financial Advocates Investment Management
Washington
$306K +$5.52K +68 +2%
Wolverine Trading
434
Wolverine Trading
Illinois
$304K -$4.47M -52,903 -94%
ATC
435
Advantage Trust Company
Kansas
$304K -$73K -900 -19%
NCM
436
NCM Capital Management
New Jersey
$301K -$4.06K -50 -1%
GWM
437
Geneos Wealth Management
Colorado
$297K +$200K +2,471 +207%
IFPG
438
Intrepid Financial Planning Group
Indiana
$297K -$28.4K -350 -9%
Luther King Capital Management (LKCM)
439
Luther King Capital Management (LKCM)
Texas
$296K -$397K – –
CIA
440
Compass Ion Advisors
Pennsylvania
$291K -$20K -247 -6%
AWM
441
Aries Wealth Management
Maine
$290K +$19.5K +240 +7%
SGCA
442
Steel Grove Capital Advisors
Tennessee
$290K -$195K -2,400 -40%
RWP
443
RWA Wealth Partners
Massachusetts
$287K -$1.22K -15 -0.4%
BFA
444
Beaumont Financial Advisors
Massachusetts
$285K – – –
HCMG
445
Howard Capital Management Group
California
$284K -$20.3M -250,661 -99%
RSWM
446
Robertson Stephens Wealth Management
California
$281K -$14.7K -181 -5%
WA
447
Wealth Alliance
New York
$280K -$51.6K -636 -16%
MIM
448
Miller Investment Management
Pennsylvania
$279K – – –
PWA
449
Prairie Wealth Advisors
Nebraska
$275K -$67.5K -832 -20%
Belvedere Trading
450
Belvedere Trading
Illinois
$274K +$274K +3,379 New
16 17
18
19 20