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State Street SPDR S&P Biotech ETF

812 hedge funds and large institutions have $16.5B invested in State Street SPDR S&P Biotech ETF in 2025 Q4 according to their latest regulatory filings, with 230 funds opening new positions, 232 increasing their positions, 204 reducing their positions, and 53 closing their positions.

New
Increased
Maintained
Reduced
Closed

334% more first-time investments, than exits

New positions opened: 230 | Existing positions closed: 53

33% more capital invested

Capital invested by funds: $12.4B → $16.5B (+$4.06B)

24% more funds holding

Funds holding: 655812 (+157)

14% more repeat investments, than reductions

Existing positions increased: 232 | Existing positions reduced: 204

6% more funds holding in top 10

Funds holding in top 10: 1819 (+1)

15.4% less ownership

Funds ownership: 214.61%199.2% (-15%)

51% less call options, than puts

Call options by funds: $3.12B | Put options by funds: $6.42B

Holders
812
Holders Change
+157
Holders Change %
+23.97%
% of All Funds
9.88%
Holding in Top 10
19
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+5.56%
% of All Funds
0.23%
New
230
Increased
232
Reduced
204
Closed
53
Calls
$3.12B
Puts
$6.42B
Net Calls
-$3.31B
Net Calls Change
-$2.53B
Name Holding Trade Value Shares
Change
Change in
Stake
PFA
376
Petra Financial Advisors
Colorado
$745K -$56.8K -495 -7%
EWA
377
EP Wealth Advisors
California
$745K +$700K +6,108 New
FCM
378
Fell Capital Management
California
$744K +$699K +6,100 New
ABC
379
Associated Banc-Corp
Wisconsin
$742K +$185K +1,613 +36%
AAP
380
Arax Advisory Partners
Colorado
$738K +$694K +6,055 New
MAMU
381
Myriad Asset Management US
Florida
$737K +$693K +6,045 New
PNAA
382
Pictet North America Advisors
Switzerland
$734K +$690K +6,020 New
CMANY
383
Capital Management Associates (New York)
New York
$732K +$688K +6,000 New
IAMH
384
IvyRock Asset Management (HK)
Hong Kong
$732K +$688K +6,000 New
SFP
385
Shepherd Financial Partners
Massachusetts
$724K -$75K -654 -10%
IA
386
Integrity Alliance
Iowa
$723K +$680K +5,932 New
AWF
387
Alpha Wealth Funds
Utah
$719K -$25K -218 -4%
KWM
388
Kingsview Wealth Management
Oregon
$713K +$3.55K +31 +0.5%
PP
389
Patten & Patten
Tennessee
$710K
EFS
390
Essex Financial Services
Connecticut
$704K +$146K +1,269 +28%
CA
391
CWC Advisors
Oregon
$694K -$1.83K -16 -0.3%
EAM
392
Empirical Asset Management
Massachusetts
$690K
TAM
393
Titleist Asset Management
Texas
$684K -$9.29K -81 -1%
GC
394
Grimes & Company
Massachusetts
$674K +$314K +2,742 +98%
Pictet Asset Management
395
Pictet Asset Management
Switzerland
$669K +$629K +5,485 New
CA
396
Calton & Associates
Florida
$663K +$23K +201 +4%
BAM
397
Byrne Asset Management
New Jersey
$658K +$619K +5,399 New
BHA
398
Beech Hill Advisors
New York
$658K -$41.3K -360 -6%
GFG
399
Greystone Financial Group
Michigan
$658K +$619K +5,395 New
AWM
400
Apollon Wealth Management
South Carolina
$656K +$330K +2,880 +115%