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State Street SPDR S&P Biotech ETF

652 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 150 increasing their positions, 242 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

5% more funds holding

Funds holding: 621652 (+31)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 150 | Existing positions reduced: 242

Holders
652
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
PCTC
376
Perkins Coie Trust Company
Washington
$429K
WAM
377
Worth Asset Management
Texas
$427K
PIA
378
Powell Investment Advisors
Florida
$425K
ATC
379
Advantage Trust Company
Kansas
$425K
HWA
380
Hillcrest Wealth Advisors
New Jersey
$425K
Bank of New York Mellon
381
Bank of New York Mellon
New York
$424K
SIC
382
Salem Investment Counselors
North Carolina
$418K
ATPW
383
Ashton Thomas Private Wealth
Arizona
$417K
AAS
384
Ameritas Advisory Services
Nebraska
$411K
GC
385
Gruss & Co
Florida
$401K
ISL
386
Ingalls & Snyder LLC
New York
$400K
CA
387
Continuum Advisory
Idaho
$398K
BO
388
Bank OZK
Arkansas
$398K
WSC
389
Wellington Shields & Co
New York
$391K
MBT
390
Montecito Bank & Trust
California
$391K
NFG
391
Nations Financial Group
Iowa
$387K
NW
392
NewEdge Wealth
Pennsylvania
$383K
CIA
393
Compass Ion Advisors
Pennsylvania
$380K
EP
394
Edgestream Partners
New Jersey
$377K
AAM
395
Ameraudi Asset Management
New York
$375K
LI
396
LMCG Investments
Massachusetts
$373K
SWP
397
Stratos Wealth Partners
Ohio
$371K
KPWS
398
Kestra Private Wealth Services
Texas
$370K
PHS
399
Pekin Hardy Strauss
Illinois
$369K
FA
400
Fiduciary Alliance
South Carolina
$364K