XBI icon

SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
LFAS
326
Level Four Advisory Services
Texas
$548K +$51.8K +639 +10%
WS
327
Wedbush Securities
California
$542K +$7.71K +95 +1%
MWM
328
Melfa Wealth Management
Massachusetts
$539K – – –
BHA
329
Beech Hill Advisors
New York
$539K -$1.22K -15 -0.2%
MCM
330
MAI Capital Management
Ohio
$537K +$31.3K +386 +6%
PP
331
Patten & Patten
Tennessee
$532K +$32.5K +401 +7%
MC
332
Mathes Company
New York
$531K -$89.2K -1,100 -14%
BWM
333
BigSur Wealth Management
Florida
$527K – – –
SF
334
Synovus Financial
Georgia
$527K -$7.63K -94 -1%
CAM
335
Cresset Asset Management
Illinois
$525K +$308K +3,797 +142%
CWM
336
Cornerstone Wealth Management
Missouri
$524K +$55.5K +684 +12%
FHC
337
First Heartland Consultants
Missouri
$514K +$13.6K +168 +3%
NAMP
338
NorthStar Asset Management (Pennsylvania)
Pennsylvania
$513K -$79.1K -975 -13%
SF
339
Summit Financial
New Jersey
$512K -$5.92K -73 -1%
EFMC
340
Empire Financial Management Company
New York
$505K -$73K -900 -13%
MIC
341
Maxi Investments CY
Cyprus
$503K -$571K -7,034 -53%
1WA
342
180 Wealth Advisors
Washington
$502K +$158K +1,953 +46%
WIM
343
Westside Investment Management
California
$500K – – –
CGL
344
Clarius Group LLC
Washington
$499K +$8.11K +100 +2%
PIMG
345
Patriot Investment Management Group
Tennessee
$497K +$5.03K +62 +1%
QC
346
Quantessence Capital
New York
$486K -$4.74M -58,426 -91%
KWM
347
Kingsview Wealth Management
Oregon
$485K -$29.6K -365 -6%
FA
348
Fortis Advisors
Pennsylvania
$483K – – –
KJHP
349
K.J. Harrison & Partners
Ontario, Canada
$470K -$1.46M -18,000 -76%
HSA
350
HBK Sorce Advisory
Pennsylvania
$470K +$106K +1,310 +29%
12 13
14
15 16