XBI icon

State Street SPDR S&P Biotech ETF

652 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 150 increasing their positions, 242 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

5% more funds holding

Funds holding: 621652 (+31)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 150 | Existing positions reduced: 242

Holders
652
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
XT
276
XTX Topco
Cayman Islands
$830K
TSW
277
Thompson Siegel & Walmsley
Virginia
$802K
SFS
278
Sowell Financial Services
Arkansas
$787K
CVM
279
Cheviot Value Management
California
$787K
PMA
280
Prudent Man Advisors
Illinois
$780K
MIG
281
McGuire Investment Group
Rhode Island
$777K
CWM
282
Cornerstone Wealth Management
Missouri
$762K
FFA
283
Farther Finance Advisors
California
$755K
CFG
284
Citizens Financial Group
Rhode Island
$754K
AQR Capital Management
285
AQR Capital Management
Connecticut
$740K
VNA
286
Valley National Advisers
Pennsylvania
$736K
GPA
287
Guerra Pan Advisors
New Jersey
$733K
SFI
288
SPC Financial Inc
Maryland
$730K
TYCC
289
Texas Yale Capital Corp
Florida
$724K
PS
290
Principal Securities
Iowa
$713K
Northern Trust
291
Northern Trust
Illinois
$704K
BAM
292
Belpointe Asset Management
Nevada
$701K
PCIG
293
Partners Capital Investment Group
Massachusetts
$695K
PGFC
294
Peapack-Gladstone Financial Corp
New Jersey
$674K
ATC
295
Argent Trust Co
Tennessee
$672K
ECM
296
Evergreen Capital Management
Washington
$670K
BLFG
297
Brian Low Financial Group
Louisiana
$668K
CH
298
Canton Hathaway
Rhode Island
$666K
MWM
299
Melfa Wealth Management
Massachusetts
$666K
PWM
300
Perigon Wealth Management
California
$662K