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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
GWM
276
Greenwich Wealth Management
Connecticut
$846K -$43.4K -536 -5%
C
277
Certuity
Florida
$830K -$76.2K -939 -8%
DAS
278
Dynamic Advisor Solutions
Arizona
$825K +$825K +10,175 New
DADC
279
D.A. Davidson & Co
Montana
$818K -$15K -185 -2%
ATC
280
Argent Trust Co
Tennessee
$818K -$11.8K -146 -1%
Wealthfront Advisers
281
Wealthfront Advisers
California
$815K -$90.4K -1,115 -10%
PA
282
Pinnacle Associates
New York
$813K -$28.4K -350 -3%
QGA
283
Q Global Advisors
Texas
$811K +$811K +10,000 New
AI
284
Atria Investments
North Carolina
$804K -$12.2K -151 -2%
RIL
285
Rothschild Investment LLC
Illinois
$792K +$9.41K +116 +1%
WAS
286
Wealth Advisory Solutions
Indiana
$787K +$62.5K +771 +9%
IFWM
287
Institute for Wealth Management
Colorado
$785K +$15.1K +186 +2%
National Bank of Canada
288
National Bank of Canada
Quebec, Canada
$781K -$267K -3,292 -25%
FWP
289
Firethorn Wealth Partners
Georgia
$778K +$60.9K +751 +8%
AR
290
Advisory Research
Illinois
$777K +$2.11K +26 +0.3%
LA
291
LM Advisors
California
$749K +$11.5K +142 +2%
Bank of Nova Scotia
292
Bank of Nova Scotia
Ontario, Canada
$744K -$2.38M -29,352 -76%
NDSI
293
Newman Dignan & Sheerar Inc
Rhode Island
$736K -$136K -1,675 -16%
NFSG
294
Newbridge Financial Services Group
Florida
$725K -$133K -1,639 -15%
CH
295
Canton Hathaway
Rhode Island
$717K -$682K -8,415 -49%
AWF
296
Alpha Wealth Funds
Utah
$714K -$585K -7,209 -45%
LP
297
LMR Partners
United Kingdom
$705K +$705K +8,692 New
MFIM
298
Mesirow Financial Investment Management
Illinois
$698K -$119K -1,469 -15%
SWM
299
Shelton Wealth Management
Texas
$698K +$345K +4,252 +98%
VIM
300
Vista Investment Management
Pennsylvania
$693K -$72.7K -897 -9%
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