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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
DMKJ
251
David M. Knott Jr
$1.11M +$295K +3,643 +36%
PS
252
Principal Securities
Iowa
$1.1M +$6.21K +69 +0.6%
NL
253
NVWM LLC
Pennsylvania
$1.07M +$109K +1,344 +11%
STA
254
Summit Trail Advisors
New York
$1.03M +$239K +2,941 +30%
MIC
255
Meridian Investment Counsel
California
$1.03M +$2.35K +29 +0.2%
TSS
256
Two Sigma Securities
New York
$1.02M +$363K +4,472 +55%
FTUS
257
Flow Traders U.S.
New York
$1.02M +$1.02M +12,535 New
CIA
258
Choate Investment Advisors
Massachusetts
$1.01M -$763K -9,411 -43%
FWM
259
FFT Wealth Management
Pennsylvania
$996K -$391K -4,816 -28%
CI
260
CX Institutional
Indiana
$989K – – –
AWS
261
Atria Wealth Solutions
New York
$982K -$198K -2,438 -17%
LP
262
LGL Partners
Pennsylvania
$968K -$521K -6,418 -35%
VWA
263
Visionary Wealth Advisors
Illinois
$964K +$156K +1,920 +19%
PMA
264
Prudent Man Advisors
Illinois
$958K – – –
TFCP
265
Twin Focus Capital Partners
Massachusetts
$957K -$1.19M -14,680 -55%
HWAM
266
Hennion & Walsh Asset Management
New Jersey
$955K +$599K +7,391 +168%
SMFG
267
Sumitomo Mitsui Financial Group
Japan
$943K -$6.41K -79 -0.7%
ASN
268
Advisory Services Network
Georgia
$940K -$155K -1,906 -14%
GKWIM
269
Gerber Kawasaki Wealth & Investment Management
California
$928K -$120K -1,480 -11%
AAS
270
Ameritas Advisory Services
Nebraska
$903K -$9.48K -111 -1%
YC
271
Yarbrough Capital
Tennessee
$900K -$2.13M -26,240 -70%
PWP
272
Pursue Wealth Partners
California
$888K -$313K -3,856 -26%
IP
273
Intellectus Partners
California
$887K -$18.2K -225 -2%
ABC
274
Associated Banc-Corp
Wisconsin
$870K -$70.5K -869 -7%
CAPTRUST Financial Advisors
275
CAPTRUST Financial Advisors
North Carolina
$870K -$1.07M -13,208 -55%
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