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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

671 hedge funds and large institutions have $9.23B invested in SPDR S&P Biotech ETF in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 176 increasing their positions, 269 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
671
Holders Change
-60
Holders Change %
-8.21%
% of All Funds
9.11%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.2%
New
72
Increased
176
Reduced
269
Closed
120
Calls
$1.08B
Puts
$2.17B
Net Calls
-$1.09B
Net Calls Change
+$169M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$294M
2
Goldman Sachs
Goldman Sachs
New York
+$287M
3
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$269M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$191M
5
MIFH
Migdal Insurance & Financial Holdings
Israel
+$85.2M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$167M
2
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$145M
3
BCM
BlueCrest Capital Management
Jersey
-$138M
4
RCM
RA Capital Management
Massachusetts
-$111M
5
Citadel Advisors
Citadel Advisors
Florida
-$61M
Name Holding Trade Value Shares
Change 		Shares
Change %
Mercer Global Advisors
226
Mercer Global Advisors
Colorado
$1.34M +$304K +3,751 +29%
AC
227
ASB Consultores
Florida
$1.33M – – –
AWA
228
Arkadios Wealth Advisors
Georgia
$1.31M +$785K +9,675 +150%
MA
229
Mutual Advisors
Nebraska
$1.31M -$49.8K -621 -4%
GA
230
GFS Advisors
Texas
$1.31M -$131K -1,612 -9%
SCA
231
STALEY CAPITAL ADVISERS
Pennsylvania
$1.3M -$157K -1,930 -11%
Bank Julius Baer & Co
232
Bank Julius Baer & Co
Switzerland
$1.27M +$66.2K +722 +5%
SB
233
SIG Brokerage
New York
$1.26M +$1.26M +15,560 New
TRCT
234
Tower Research Capital (TRC)
New York
$1.26M -$8.75M -94,107 -87%
VNA
235
Valley National Advisers
Pennsylvania
$1.25M -$99.3K -1,225 -7%
Parallax Volatility Advisers
236
Parallax Volatility Advisers
California
$1.24M -$24.4M -300,666 -95%
Northern Trust
237
Northern Trust
Illinois
$1.23M +$154K +1,898 +14%
UM
238
Ulysses Management
New York
$1.22M – – –
LWM
239
LJI Wealth Management
Indiana
$1.2M +$96.9K +1,195 +9%
PI
240
PFG Investments
New York
$1.19M -$52K -641 -4%
EWA
241
Evolution Wealth Advisors
Florida
$1.18M -$1.26M -15,545 -52%
LWM
242
Lyell Wealth Management
California
$1.18M -$451K -5,566 -28%
PA
243
PFG Advisors
Arizona
$1.17M -$461K -5,681 -28%
MIA
244
MeadowBrook Investment Advisors
Michigan
$1.16M -$8.11K -100 -0.7%
AMI
245
Amica Mutual Insurance
Rhode Island
$1.15M – – –
SPIA
246
Steward Partners Investment Advisory
New York
$1.14M +$11.8K +145 +1%
PCM
247
Prelude Capital Management
New York
$1.14M +$1.14M +14,014 New
SG
248
Sharper & Granite
California
$1.13M +$148K +1,830 +15%
PCIG
249
Partners Capital Investment Group
Massachusetts
$1.12M +$562K +6,934 +100%
MCP
250
Militia Capital Partners
Nevada
$1.12M +$504K +6,220 +81%
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