|
1
|
Aquilo Capital Management
San Francisco,
California
|
$6.81M
|
-$1.91M
|
-1,918,021
|
-36%
|
|
|
2
|
AWM Investment Company
New York
|
$4.6M
|
+$2.29M
|
+2,300,400
|
New
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$3.86M
|
-$1.15M
|
-1,160,239
|
-38%
|
|
|
4
|
Anson Funds Management
Dallas,
Texas
|
$2.95M
|
+$1.47M
|
+1,473,872
|
New
|
|
|
5
|
Atlas Venture Associates IX
Boston,
Massachusetts
|
$2.75M
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.11M
|
-$191K
|
-192,269
|
-15%
|
|
|
7
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$2.06M
|
–
|
–
|
–
|
|
|
8
|
Alphabet Inc
Mountain View,
California
|
$1.78M
|
–
|
–
|
–
|
|
|
9
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$1.54M
|
–
|
–
|
–
|
|
|
10
|
Murchinson
Toronto,
Ontario, Canada
|
$1.52M
|
+$758K
|
+762,700
|
New
|
|
|
11
|
|
$1.39M
|
+$1.38K
|
+1,385
|
+0.2%
|
|
|
12
|
Millennium Management
New York
|
$1.38M
|
+$372K
|
+373,753
|
+119%
|
|
|
13
|
|
$1M
|
–
|
–
|
–
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$938K
|
–
|
–
|
–
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$580K
|
–
|
–
|
–
|
|
|
16
|
Oasis Management Company
Grand Cayman,
Cayman Islands
|
$576K
|
–
|
–
|
–
|
|
|
17
|
OUP Management Company
Bala Cynwyd,
Pennsylvania
|
$498K
|
–
|
–
|
–
|
|
|
18
|
Renaissance Technologies
New York
|
$429K
|
-$720K
|
-724,317
|
-77%
|
|
|
19
|
Bank of Montreal
Toronto,
Ontario, Canada
|
$415K
|
+$201K
|
+202,300
|
New
|
|
|
20
|
Marshall Wace
London,
United Kingdom
|
$374K
|
+$149K
|
+150,201
|
+413%
|
|
|
21
|
AQR Capital Management
Greenwich,
Connecticut
|
$373K
|
+$31K
|
+31,208
|
+20%
|
|
|
22
|
DAFNA Capital Management
Los Angeles,
California
|
$250K
|
+$124K
|
+125,000
|
New
|
|
|
23
|
State Street
Boston,
Massachusetts
|
$183K
|
-$9.02K
|
-9,073
|
-9%
|
|
|
24
|
Letko, Brosseau & Associates
Montreal,
Quebec, Canada
|
$147K
|
–
|
–
|
–
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$140K
|
-$5
|
-5
|
-0%
|
|
