|
1
|
Aquilo Capital Management
San Francisco,
California
|
$45.9M
|
+$3.25M
|
+317,323
|
+6%
|
|
|
2
|
|
$15.6M
|
-$48.1K
|
-4,696
|
-0.3%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$13.8M
|
–
|
–
|
–
|
|
|
4
|
Atlas Venture Associates IX
Boston,
Massachusetts
|
$12M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$12M
|
+$231K
|
+22,550
|
+2%
|
|
|
6
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$8.97M
|
–
|
–
|
–
|
|
|
7
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$8.62M
|
+$467K
|
+45,600
|
+5%
|
|
|
8
|
Alphabet Inc
Mountain View,
California
|
$7.74M
|
–
|
–
|
–
|
|
|
9
|
Ameriprise
Minneapolis,
Minnesota
|
$5.1M
|
+$2.29M
|
+223,108
|
+61%
|
|
|
10
|
|
$4.35M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$4.33M
|
-$3.55M
|
-346,770
|
-41%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$4.1M
|
+$143K
|
+14,005
|
+3%
|
|
|
13
|
Novo Holdings A/S
Hellerup,
Denmark
|
$4.08M
|
–
|
–
|
–
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$3.54M
|
+$366K
|
+35,724
|
+10%
|
|
|
15
|
Osaic Holdings
Scottsdale,
Arizona
|
$3.47M
|
-$307
|
-30
|
-3%
|
|
|
16
|
AWM Investment Company
New York
|
$3.24M
|
–
|
–
|
–
|
|
|
17
|
OUP Management Company
Bala Cynwyd,
Pennsylvania
|
$2.17M
|
–
|
–
|
–
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$2.07M
|
-$151K
|
-14,748
|
-6%
|
|
|
19
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$1.71M
|
+$138K
|
+13,502
|
+7%
|
|
|
20
|
|
$1.23M
|
+$28.8K
|
+2,815
|
+2%
|
|
|
21
|
Granahan Investment Management
Waltham,
Massachusetts
|
$986K
|
-$2.72M
|
-265,610
|
-70%
|
|
|
22
|
Renaissance Technologies
New York
|
$949K
|
+$1.12M
|
+109,100
|
New
|
|
|
23
|
|
$706K
|
-$164K
|
-16,013
|
-16%
|
|
|
24
|
Two Sigma Investments
New York
|
$686K
|
+$808K
|
+78,908
|
New
|
|
|
25
|
Letko, Brosseau & Associates
Montreal,
Quebec, Canada
|
$641K
|
–
|
–
|
–
|
|
