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Spero Therapeutics

Name Holding Trade Value Shares
Change
Change in
Stake
ACM
1
Aquilo Capital Management
California
$84M +$11.8M +734,479 +19%
BI
2
BVF Inc
California
$33.3M -$5.27M -328,626 -15%
BlackRock
3
BlackRock
New York
$33.2M +$380K +23,706 +1%
AVAI
4
Atlas Venture Associates IX
Massachusetts
$25.4M
Vanguard Group
5
Vanguard Group
Pennsylvania
$23.8M +$252K +15,708 +1%
RSCM
6
Rock Springs Capital Management
Maryland
$17.3M -$391K -24,385 -3%
AI
7
Alphabet Inc
California
$16.4M
State Street
8
State Street
Massachusetts
$14.8M -$129K -8,047 -1%
GIM
9
Granahan Investment Management
Massachusetts
$10.2M +$3.58M +222,975 +67%
AG
10
Artal Group
Luxembourg
$9.21M
NHAS
11
Novo Holdings A/S
Denmark
$8.63M
Geode Capital Management
12
Geode Capital Management
Massachusetts
$8.19M +$500K +31,153 +8%
Ameriprise
13
Ameriprise
Minnesota
$6.94M -$991K -61,742 -14%
AIC
14
AWM Investment Company
New York
$6.86M
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$6.07M -$719K -44,810 -12%
Northern Trust
16
Northern Trust
Illinois
$4.75M -$47.3K -2,947 -1%
Royal Bank of Canada
17
Royal Bank of Canada
Ontario, Canada
$3.32M +$2.86M +177,945 +8,250%
Goldman Sachs
18
Goldman Sachs
New York
$2.53M +$21.1K +1,317 +1%
WJWM
19
Williams Jones Wealth Management
New York
$1.94M +$1.69M +105,500 New
JP Morgan Chase
20
JP Morgan Chase
New York
$1.93M -$175K -10,922 -9%
Bank of New York Mellon
21
Bank of New York Mellon
New York
$1.37M +$122K +7,612 +11%
Nuveen
22
Nuveen
North Carolina
$1.36M +$114K +7,079 +11%
LBA
23
Letko, Brosseau & Associates
Quebec, Canada
$1.36M
New York State Common Retirement Fund
24
New York State Common Retirement Fund
New York
$1.31M +$342K +21,329 +43%
Charles Schwab
25
Charles Schwab
California
$1.17M +$49.6K +3,090 +5%