|
1
|
Aquilo Capital Management
San Francisco,
California
|
$53.5M
|
–
|
–
|
–
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$29.8M
|
–
|
–
|
–
|
|
|
3
|
|
$24.8M
|
+$31.1K
|
+2,226
|
+0.1%
|
|
|
4
|
Atlas Venture Associates IX
Boston,
Massachusetts
|
$19.2M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$17.8M
|
+$2.38M
|
+170,094
|
+15%
|
|
|
6
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$13.5M
|
–
|
–
|
–
|
|
|
7
|
Alphabet Inc
Mountain View,
California
|
$12.4M
|
–
|
–
|
–
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$11.3M
|
-$7.63M
|
-545,805
|
-40%
|
|
|
9
|
|
$6.98M
|
–
|
–
|
–
|
|
|
10
|
Novo Holdings A/S
Hellerup,
Denmark
|
$6.55M
|
–
|
–
|
–
|
|
|
11
|
Ameriprise
Minneapolis,
Minnesota
|
$6.13M
|
+$56.6K
|
+4,049
|
+0.9%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$5.78M
|
+$701K
|
+50,150
|
+14%
|
|
|
13
|
Dimensional Fund Advisors
Austin,
Texas
|
$5.23M
|
+$446K
|
+31,937
|
+9%
|
|
|
14
|
AWM Investment Company
New York
|
$5.2M
|
–
|
–
|
–
|
|
|
15
|
Granahan Investment Management
Waltham,
Massachusetts
|
$4.64M
|
-$132K
|
-9,474
|
-3%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$3.64M
|
+$298K
|
+21,308
|
+9%
|
|
|
17
|
|
$1.9M
|
-$1.67M
|
-119,538
|
-47%
|
|
|
18
|
|
$1.62M
|
+$661K
|
+47,287
|
+69%
|
|
|
19
|
Letko, Brosseau & Associates
Montreal,
Quebec, Canada
|
$1.03M
|
–
|
–
|
–
|
|
|
20
|
|
$974K
|
-$1.67M
|
-119,177
|
-63%
|
|
|
21
|
Bank of New York Mellon
New York
|
$930K
|
+$47.8K
|
+3,423
|
+5%
|
|
|
22
|
Nuveen
Charlotte,
North Carolina
|
$894K
|
-$4.3K
|
-308
|
-0.5%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$845K
|
+$100K
|
+7,138
|
+13%
|
|
|
24
|
New York State Common Retirement Fund
Albany,
New York
|
$696K
|
-$121K
|
-8,638
|
-15%
|
|
|
25
|
Stifel Financial
St. Louis,
Missouri
|
$685K
|
+$6.99K
|
+500
|
+1%
|
|
