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Spero Therapeutics

Name Holding Trade Value Shares
Change
Change in
Stake
ACM
1
Aquilo Capital Management
California
$53.5M
BI
2
BVF Inc
California
$29.8M
BlackRock
3
BlackRock
New York
$24.8M +$31.1K +2,226 +0.1%
AVAI
4
Atlas Venture Associates IX
Massachusetts
$19.2M
Vanguard Group
5
Vanguard Group
Pennsylvania
$17.8M +$2.38M +170,094 +15%
RSCM
6
Rock Springs Capital Management
Maryland
$13.5M
AI
7
Alphabet Inc
California
$12.4M
State Street
8
State Street
Massachusetts
$11.3M -$7.63M -545,805 -40%
AG
9
Artal Group
Luxembourg
$6.98M
NHAS
10
Novo Holdings A/S
Denmark
$6.55M
Ameriprise
11
Ameriprise
Minnesota
$6.13M +$56.6K +4,049 +0.9%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$5.78M +$701K +50,150 +14%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$5.23M +$446K +31,937 +9%
AIC
14
AWM Investment Company
New York
$5.2M
GIM
15
Granahan Investment Management
Massachusetts
$4.64M -$132K -9,474 -3%
Northern Trust
16
Northern Trust
Illinois
$3.64M +$298K +21,308 +9%
Goldman Sachs
17
Goldman Sachs
New York
$1.9M -$1.67M -119,538 -47%
JP Morgan Chase
18
JP Morgan Chase
New York
$1.62M +$661K +47,287 +69%
LBA
19
Letko, Brosseau & Associates
Quebec, Canada
$1.03M
Morgan Stanley
20
Morgan Stanley
New York
$974K -$1.67M -119,177 -63%
Bank of New York Mellon
21
Bank of New York Mellon
New York
$930K +$47.8K +3,423 +5%
Nuveen
22
Nuveen
North Carolina
$894K -$4.3K -308 -0.5%
Charles Schwab
23
Charles Schwab
California
$845K +$99.7K +7,138 +13%
New York State Common Retirement Fund
24
New York State Common Retirement Fund
New York
$696K -$121K -8,638 -15%
Stifel Financial
25
Stifel Financial
Missouri
$685K +$6.99K +500 +1%