|
1
|
Aquilo Capital Management
San Francisco,
California
|
$79.5M
|
+$6.36M
|
+400,493
|
+9%
|
|
|
2
|
|
$28.8M
|
-$59.6K
|
-3,751
|
-0.2%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$25.4M
|
-$3.55M
|
-223,737
|
-12%
|
|
|
4
|
Atlas Venture Associates IX
Boston,
Massachusetts
|
$22M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$21.6M
|
+$935K
|
+58,880
|
+5%
|
|
|
6
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$16.5M
|
+$16.4M
|
+1,031,160
|
New
|
|
|
7
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$15.1M
|
+$59.9K
|
+3,770
|
+0.4%
|
|
|
8
|
Alphabet Inc
Mountain View,
California
|
$14.2M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$13.5M
|
+$655K
|
+41,264
|
+5%
|
|
|
10
|
|
$8.01M
|
–
|
–
|
–
|
|
|
11
|
Novo Holdings A/S
Hellerup,
Denmark
|
$7.51M
|
–
|
–
|
–
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$7.32M
|
+$195K
|
+12,270
|
+3%
|
|
|
13
|
Granahan Investment Management
Waltham,
Massachusetts
|
$6.07M
|
-$2.81M
|
-176,682
|
-32%
|
|
|
14
|
AWM Investment Company
New York
|
$5.97M
|
–
|
–
|
–
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
$5.94M
|
+$661K
|
+41,589
|
+13%
|
|
|
16
|
Ameriprise
Minneapolis,
Minnesota
|
$5.82M
|
-$215K
|
-13,561
|
-4%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$4.05M
|
-$75.3K
|
-4,739
|
-2%
|
|
|
18
|
OUP Management Company
Bala Cynwyd,
Pennsylvania
|
$3.99M
|
+$3.96M
|
+249,070
|
New
|
|
|
19
|
Royal Bank of Canada
Toronto,
Ontario, Canada
|
$2.92M
|
+$39.6K
|
+2,493
|
+1%
|
|
|
20
|
|
$2.22M
|
+$16.4K
|
+1,032
|
+0.8%
|
|
|
21
|
|
$1.56M
|
-$123K
|
-7,749
|
-7%
|
|
|
22
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$1.2M
|
+$563K
|
+35,435
|
+89%
|
|
|
23
|
Williams Jones Wealth Management
New York
|
$1.2M
|
-$484K
|
-30,500
|
-29%
|
|
|
24
|
Bank of New York Mellon
New York
|
$1.2M
|
+$12.6K
|
+793
|
+1%
|
|
|
25
|
Letko, Brosseau & Associates
Montreal,
Quebec, Canada
|
$1.18M
|
–
|
–
|
–
|
|
