|
1
|
BVF Inc
San Francisco,
California
|
$15.6M
|
+$5.1M
|
+439,130
|
+42%
|
|
|
2
|
Atlas Venture Associates IX
Boston,
Massachusetts
|
$14.5M
|
–
|
–
|
–
|
|
|
3
|
Alphabet Inc
Mountain View,
California
|
$11.7M
|
–
|
–
|
–
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$9.38M
|
+$10.4M
|
+892,741
|
New
|
|
|
5
|
Aquilo Capital Management
San Francisco,
California
|
$8.4M
|
+$4.44M
|
+383,000
|
+92%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$6.5M
|
-$2.11M
|
-181,794
|
-23%
|
|
|
7
|
|
$6.31M
|
+$2.9M
|
+250,000
|
+71%
|
|
|
8
|
AWM Investment Company
New York
|
$5.68M
|
+$4.64M
|
+400,000
|
+285%
|
|
|
9
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$5.52M
|
–
|
–
|
–
|
|
|
10
|
VHCP Management II
New York
|
$4.98M
|
–
|
–
|
–
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.79M
|
+$3.84M
|
+330,580
|
+265%
|
|
|
12
|
|
$3.92M
|
+$354K
|
+30,470
|
+9%
|
|
|
13
|
Stonepine Capital Management
Bend,
Oregon
|
$2.38M
|
+$2.63M
|
+226,444
|
New
|
|
|
14
|
|
$1.85M
|
+$439K
|
+37,840
|
+27%
|
|
|
15
|
UBS O'Connor
Chicago,
Illinois
|
$1.79M
|
+$1.97M
|
+170,000
|
New
|
|
|
16
|
Granahan Investment Management
Waltham,
Massachusetts
|
$1.65M
|
+$68.6K
|
+5,910
|
+4%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$1.34M
|
+$774K
|
+66,727
|
+109%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$1.01M
|
+$338K
|
+29,145
|
+44%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$924K
|
+$400K
|
+34,476
|
+64%
|
|
|
20
|
Bridgeway Capital Management
Houston,
Texas
|
$826K
|
+$277K
|
+23,879
|
+44%
|
|
|
21
|
DAFNA Capital Management
Los Angeles,
California
|
$736K
|
+$812K
|
+70,000
|
New
|
|
|
22
|
Schonfeld Strategic Advisors
New York
|
$526K
|
+$580K
|
+50,000
|
New
|
|
|
23
|
Point72 Asset Management
Stamford,
Connecticut
|
$462K
|
+$511K
|
+44,000
|
New
|
|
|
24
|
Bank of New York Mellon
New York
|
$293K
|
+$36.4K
|
+3,139
|
+13%
|
|
|
25
|
Highland Capital Management (Texas)
Dallas,
Texas
|
$210K
|
+$232K
|
+20,000
|
New
|
|
