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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

225 hedge funds and large institutions have $4.2B invested in Rhythm Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 92 increasing their positions, 73 reducing their positions, and 34 closing their positions.

Holders
225
Holders Change
-3
Holders Change %
-1.32%
% of All Funds
3.02%
Holding in Top 10
10
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+42.86%
% of All Funds
0.13%
New
34
Increased
92
Reduced
73
Closed
34
Calls
$9.98M
Puts
$28.3M
Net Calls
-$18.3M
Net Calls Change
-$36.3M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$79M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$49.5M
3
WP
3
Woodline Partners
California
$32.5M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.5M
5
ClearBridge Investments
5
ClearBridge Investments
New York
$19.7M

Top Sellers

1
Primecap Management
1
Primecap Management
California
$308M
2
BlackRock
2
BlackRock
New York
$396M
3
FLSM
3
Frazier Life Sciences Management
California
$0
4
RCM
4
RA Capital Management
Massachusetts
$351M
5
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$3.42M
Name Market Value Shares Shares
Change 		Shares
Change %
Morgan Stanley
26
Morgan Stanley
New York
$33.1M 524,480 +20,431 +4%
WP
27
Woodline Partners
California
$32.5M 514,381 +514,381 New
Northern Trust
28
Northern Trust
Illinois
$32.2M 510,246 -25,960 -5%
OM
29
Opaleye Management
Massachusetts
$30M 475,000 -15,000 -3%
Charles Schwab
30
Charles Schwab
California
$29.2M 461,438 +16,009 +4%
Pictet Asset Management
31
Pictet Asset Management
Switzerland
$26.3M 416,115 +156,769 +60%
SL
32
Siren LLC
Connecticut
$25.9M 409,742 +132,209 +48%
SCM
33
Silverarc Capital Management
Massachusetts
$25.3M 400,772 +63,167 +19%
Marshall Wace
34
Marshall Wace
United Kingdom
$23.8M 376,242 -158,861 -30%
Barclays
35
Barclays
United Kingdom
$22.2M 351,198 +249,981 +247%
Adage Capital Partners
36
Adage Capital Partners
Massachusetts
$21.5M 341,000 +341,000 New
Voloridge Investment Management
37
Voloridge Investment Management
Florida
$21.4M 338,804 -84,064 -20%
Renaissance Technologies
38
Renaissance Technologies
New York
$19.9M 314,893 +300,781 +2,131%
CS
39
Candriam SCA
Luxembourg
$19.7M 312,452 +20,983 +7%
ClearBridge Investments
40
ClearBridge Investments
New York
$19.7M 312,445 +312,445 New
Comerica Bank
41
Comerica Bank
Texas
$19.1M 301,661 +56,907 +23%
UBS Group
42
UBS Group
Switzerland
$16M 252,582 -19,526 -7%
O
43
OrbiMed
New York
$15.7M 248,512 -131,488 -35%
VOYA Investment Management
44
VOYA Investment Management
Georgia
$15.4M 244,003 +158,154 +184%
Qube Research & Technologies (QRT)
45
Qube Research & Technologies (QRT)
United Kingdom
$15.2M 240,345 +24,152 +11%
Assenagon Asset Management
46
Assenagon Asset Management
Luxembourg
$15M 237,998 +215,806 +972%
UBS AM
47
UBS AM
Illinois
$14.4M 227,627 +101,845 +81%
Bank of America
48
Bank of America
North Carolina
$14M 222,152 +110,400 +99%
Norges Bank
49
Norges Bank
Norway
$13.1M 207,389 +207,389 New
Lord, Abbett & Co
50
Lord, Abbett & Co
New Jersey
$12.9M 204,275 +68,915 +51%
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