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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

225 hedge funds and large institutions have $4.2B invested in Rhythm Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 92 increasing their positions, 73 reducing their positions, and 34 closing their positions.

Holders
225
Holders Change
-3
Holders Change %
-1.32%
% of All Funds
3.02%
Holding in Top 10
10
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+42.86%
% of All Funds
0.13%
New
34
Increased
92
Reduced
73
Closed
34
Calls
$9.98M
Puts
$28.3M
Net Calls
-$18.3M
Net Calls Change
-$36.3M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$79M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$49.5M
3
WP
3
Woodline Partners
California
$32.5M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.5M
5
ClearBridge Investments
5
ClearBridge Investments
New York
$19.7M

Top Sellers

1
Primecap Management
1
Primecap Management
California
$308M
2
BlackRock
2
BlackRock
New York
$396M
3
FLSM
3
Frazier Life Sciences Management
California
$0
4
RCM
4
RA Capital Management
Massachusetts
$351M
5
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$3.42M
Name Market Value Shares Shares
Change 		Shares
Change %
Manulife (Manufacturers Life Insurance)
76
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$4.31M 68,132 +3,746 +6%
Aberdeen Group
77
Aberdeen Group
United Kingdom
$4.28M 67,657 -40,472 -37%
CSS
78
Cubist Systematic Strategies
Connecticut
$4.08M 64,577 -109,245 -63%
AllianceBernstein
79
AllianceBernstein
Tennessee
$3.88M 61,470 – –
AG
80
Algert Global
California
$3.81M 60,219 -1,242 -2%
New York State Common Retirement Fund
81
New York State Common Retirement Fund
New York
$3.7M 58,618 +41,768 +248%
KCM
82
Kennedy Capital Management
Missouri
$3.62M 57,217 +2,287 +4%
TD Asset Management
83
TD Asset Management
Ontario, Canada
$3.54M 56,000 +5,800 +12%
Balyasny Asset Management
84
Balyasny Asset Management
Illinois
$3.42M 54,088 -301,624 -85%
Legal & General Group
85
Legal & General Group
United Kingdom
$3.33M 52,681 +1,523 +3%
AI
86
Axiom Investors
Connecticut
$3.31M 52,460 +52,460 New
Rafferty Asset Management
87
Rafferty Asset Management
New York
$3.26M 51,611 -6,121 -11%
HWAM
88
Hennion & Walsh Asset Management
New Jersey
$3.23M 51,079 -38,543 -43%
SB
89
Samsara BioCapital
California
$3.19M 50,476 -87,642 -63%
NFGH
90
Nan Fung Group Holdings
Hong Kong
$3.1M 49,120 – –
AQR Capital Management
91
AQR Capital Management
Connecticut
$3.1M 49,040 +9,677 +25%
SAM
92
Silvercrest Asset Management
New York
$3.08M 48,775 +48,775 New
ACM
93
ADAR1 Capital Management
Texas
$2.87M 45,390 +8,500 +23%
California State Teachers Retirement System (CalSTRS)
94
California State Teachers Retirement System (CalSTRS)
California
$2.71M 42,917 +196 +0.5%
Wells Fargo
95
Wells Fargo
California
$2.68M 42,368 -28,270 -40%
GIM
96
Granahan Investment Management
Massachusetts
$2.6M 41,172 +41,172 New
Deutsche Bank
97
Deutsche Bank
Germany
$2.32M 36,779 -7,000 -16%
State of Wisconsin Investment Board
98
State of Wisconsin Investment Board
Wisconsin
$2.26M 35,708 +2,683 +8%
DFCM
99
Dark Forest Capital Management
Puerto Rico
$2.2M 34,829 +9,420 +37%
Citigroup
100
Citigroup
New York
$2.17M 34,324 -51,882 -60%
2 3
4
5 6