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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

225 hedge funds and large institutions have $4.2B invested in Rhythm Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 92 increasing their positions, 73 reducing their positions, and 34 closing their positions.

Holders
225
Holders Change
-3
Holders Change %
-1.32%
% of All Funds
3.02%
Holding in Top 10
10
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+42.86%
% of All Funds
0.13%
New
34
Increased
92
Reduced
73
Closed
34
Calls
$9.98M
Puts
$28.3M
Net Calls
-$18.3M
Net Calls Change
-$36.3M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$79M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$49.5M
3
WP
3
Woodline Partners
California
$32.5M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.5M
5
ClearBridge Investments
5
ClearBridge Investments
New York
$19.7M

Top Sellers

1
Primecap Management
1
Primecap Management
California
$308M
2
BlackRock
2
BlackRock
New York
$396M
3
FLSM
3
Frazier Life Sciences Management
California
$0
4
RCM
4
RA Capital Management
Massachusetts
$351M
5
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$3.42M
Name Market Value Shares Shares
Change 		Shares
Change %
Millennium Management
51
Millennium Management
New York
$12.5M 198,110 -19,269 -9%
Royal Bank of Canada
52
Royal Bank of Canada
Ontario, Canada
$12.4M 196,236 +196,105 +149,698%
Bank of New York Mellon
53
Bank of New York Mellon
New York
$11.6M 184,109 +37,524 +26%
SC
54
Stempoint Capital
New York
$11.2M 176,752 +142,936 +423%
Artisan Partners
55
Artisan Partners
Wisconsin
$11M 174,479 +174,479 New
Ameriprise
56
Ameriprise
Minnesota
$10.9M 173,069 +74,788 +76%
Point72 Asset Management
57
Point72 Asset Management
Connecticut
$10.8M 170,832 +106,990 +168%
Russell Investments Group
58
Russell Investments Group
United Kingdom
$8.28M 130,998 +16,220 +14%
LGM
59
Logos Global Management
California
$8.21M 130,000 +130,000 New
NL
60
Nuveen LLC
North Carolina
$7.7M 121,855 -25,446 -17%
IHAM
61
Integral Health Asset Management
New York
$7.58M 120,000 +120,000 New
PAM
62
Panagora Asset Management
Massachusetts
$7.55M 119,466 -21,696 -15%
Connor, Clark & Lunn Investment Management (CC&L)
63
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$7.27M 115,118 +64,561 +128%
BNP Paribas Financial Markets
64
BNP Paribas Financial Markets
France
$6.46M 102,239 +16,173 +19%
Lazard Asset Management
65
Lazard Asset Management
New York
$6.28M 99,445 -3,757 -4%
PP
66
PDT Partners
New York
$6.17M 97,638 -4,557 -4%
Universal-Beteiligungs- und Servicegesellschaft
67
Universal-Beteiligungs- und Servicegesellschaft
Germany
$6.04M 95,517 +2,412 +3%
Swiss National Bank
68
Swiss National Bank
Switzerland
$5.73M 90,600 +1,300 +1%
RhumbLine Advisers
69
RhumbLine Advisers
Massachusetts
$5.53M 87,526 +1,807 +2%
HCA
70
Harbor Capital Advisors
Illinois
$5.47M 86,546 +9,249 +12%
Neuberger Berman Group
71
Neuberger Berman Group
New York
$5.44M 86,139 +18,200 +27%
SSA
72
Schonfeld Strategic Advisors
New York
$4.93M 77,983 +20,833 +36%
First Trust Advisors
73
First Trust Advisors
Illinois
$4.66M 73,714 -16,065 -18%
CCM
74
Cinctive Capital Management
New York
$4.48M 70,937 +66,581 +1,528%
Invesco
75
Invesco
Georgia
$4.36M 68,924 -192,978 -74%
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