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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $4.2B invested in Rhythm Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 92 increasing their positions, 74 reducing their positions, and 34 closing their positions.

Holders
227
Holders Change
-1
Holders Change %
-0.44%
% of All Funds
3.05%
Holding in Top 10
10
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+42.86%
% of All Funds
0.13%
New
34
Increased
92
Reduced
74
Closed
34
Calls
$13.8M
Puts
$36.7M
Net Calls
-$22.9M
Net Calls Change
-$40.9M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$79M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$49.5M
3
WP
3
Woodline Partners
California
$32.5M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.5M
5
ClearBridge Investments
5
ClearBridge Investments
New York
$19.7M

Top Sellers

1
Primecap Management
1
Primecap Management
California
$308M
2
BlackRock
2
BlackRock
New York
$396M
3
FLSM
3
Frazier Life Sciences Management
California
$0
4
RCM
4
RA Capital Management
Massachusetts
$351M
5
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$3.42M
Name Holding Trade Value Shares
Change 		Shares
Change %
AI
126
Atom Investors
Texas
$939K -$6.07K -96 -0.6%
State Board of Administration of Florida Retirement System
127
State Board of Administration of Florida Retirement System
Florida
$927K – – –
ASRS
128
Arizona State Retirement System
Arizona
$874K +$41.3K +653 +5%
AAM
129
Advisors Asset Management
Colorado
$859K +$211K +3,346 +33%
ProShare Advisors
130
ProShare Advisors
Maryland
$855K -$73.8K -1,168 -8%
LWL
131
Leo Wealth LLC
Texas
$850K -$161K -2,555 -16%
PD
132
Point72 (DIFC)
United Arab Emirates
$831K +$410K +6,496 +98%
Principal Financial Group
133
Principal Financial Group
Iowa
$826K -$1.52M -24,089 -65%
CUAMC
134
China Universal Asset Management Company
China
$807K +$6.07K +96 +0.8%
Teacher Retirement System of Texas
135
Teacher Retirement System of Texas
Texas
$807K +$23.3K +368 +3%
PFSRSONJ
136
Police & Firemen's Retirement System of New Jersey
New Jersey
$781K +$44.5K +704 +6%
Allianz Asset Management
137
Allianz Asset Management
Germany
$765K +$379K +6,000 +98%
Canada Life
138
Canada Life
Manitoba, Canada
$733K – – –
PA
139
Profund Advisors
Maryland
$711K -$75.2K -1,190 -10%
Raymond James Financial
140
Raymond James Financial
Florida
$666K +$666K +10,546 New
KK
141
KLP Kapitalforvaltning
Norway
$645K +$56.9K +900 +10%
FT
142
Fiduciary Trust
Massachusetts
$632K -$316K -5,000 -33%
CFS
143
Cannon Financial Strategists
Georgia
$632K – – –
TFA
144
Toth Financial Advisory
Virginia
$632K +$632K +10,000 New
Two Sigma Advisers
145
Two Sigma Advisers
New York
$613K -$152K -2,400 -20%
Zurich Cantonal Bank
146
Zurich Cantonal Bank
Switzerland
$610K +$45.9K +726 +8%
EOJOAM
147
E. Ohman J:or Asset Management
Sweden
$519K +$519K +8,213 New
CM
148
Caption Management
Oklahoma
$476K +$476K +7,540 New
TI
149
Trexquant Investment
Connecticut
$448K -$2M -31,641 -82%
VIA
150
Virtus Investment Advisers
Connecticut
$446K +$38.3K +606 +9%
4 5
6
7 8