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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $4.2B invested in Rhythm Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 92 increasing their positions, 74 reducing their positions, and 34 closing their positions.

Holders
227
Holders Change
-1
Holders Change %
-0.44%
% of All Funds
3.05%
Holding in Top 10
10
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+42.86%
% of All Funds
0.13%
New
34
Increased
92
Reduced
74
Closed
34
Calls
$13.8M
Puts
$36.7M
Net Calls
-$22.9M
Net Calls Change
-$40.9M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$79M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$49.5M
3
WP
3
Woodline Partners
California
$32.5M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.5M
5
ClearBridge Investments
5
ClearBridge Investments
New York
$19.7M

Top Sellers

1
Primecap Management
1
Primecap Management
California
$308M
2
BlackRock
2
BlackRock
New York
$396M
3
FLSM
3
Frazier Life Sciences Management
California
$0
4
RCM
4
RA Capital Management
Massachusetts
$351M
5
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$3.42M
Name Holding Trade Value Shares
Change 		Shares
Change %
FCH
176
Freestone Capital Holdings
Washington
$234K +$234K +3,700 New
OSAM
177
O'Shaughnessy Asset Management
Connecticut
$220K +$220K +3,476 New
Carson Wealth (CWM LLC)
178
Carson Wealth (CWM LLC)
Nebraska
$195K +$32K +507 +20%
Mirae Asset Global Investments
179
Mirae Asset Global Investments
South Korea
$155K +$21.6K +342 +16%
EWP
180
Elevation Wealth Partners
California
$125K – – –
AB
181
Amalgamated Bank
New York
$119K – – –
WT
182
Whittier Trust
California
$111K – – –
KBC Group
183
KBC Group
Belgium
$108K -$34.4K -544 -24%
GFM
184
GF Fund Management
China
$99.4K – – –
A
185
AlphaQuest
New York
$92.9K -$325K -5,137 -78%
Nisa Investment Advisors
186
Nisa Investment Advisors
Missouri
$79.2K +$885 +14 +1%
SOW
187
State of Wyoming
Wyoming
$67.3K +$67.3K +1,065 New
CA
188
Clearstead Advisors
Ohio
$37.3K +$37.3K +590 New
AAP
189
Arax Advisory Partners
Colorado
$35.3K +$2.53K +40 +8%
BNP Paribas Asset Management
190
BNP Paribas Asset Management
France
$27K +$27K +421 New
GRP
191
Global Retirement Partners
California
$25.3K +$25.3K +400 New
AG
192
AmeriFlex Group
Nevada
$22.1K – – –
Osaic Holdings
193
Osaic Holdings
Arizona
$20.2K -$14.6K -247 -42%
CLOS
194
Compagnie Lombard Odier SCmA
Switzerland
$15.8K +$15.8K +250 New
Jones Financial Companies
195
Jones Financial Companies
Missouri
$14.5K – – –
S
196
SignatureFD
Georgia
$14.2K – – –
Daiwa Securities Group
197
Daiwa Securities Group
Japan
$14K +$1.59K +26 +13%
Optiver Holding
198
Optiver Holding
Netherlands
$14K +$4.17K +66 +43%
GI
199
GAMMA Investing
California
$13.3K -$4.42K -70 -25%
FHA
200
First Horizon Advisors
Tennessee
$12.6K +$12.6K +200 New
6 7
8
9 10