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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $4.2B invested in Rhythm Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 34 funds opening new positions, 92 increasing their positions, 74 reducing their positions, and 34 closing their positions.

Holders
227
Holders Change
-1
Holders Change %
-0.44%
% of All Funds
3.05%
Holding in Top 10
10
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+42.86%
% of All Funds
0.13%
New
34
Increased
92
Reduced
74
Closed
34
Calls
$13.8M
Puts
$36.7M
Net Calls
-$22.9M
Net Calls Change
-$40.9M

Top Buyers

1
PCH
1
Polar Capital Holdings
United Kingdom
$79M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$49.5M
3
WP
3
Woodline Partners
California
$32.5M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.5M
5
ClearBridge Investments
5
ClearBridge Investments
New York
$19.7M

Top Sellers

1
Primecap Management
1
Primecap Management
California
$308M
2
BlackRock
2
BlackRock
New York
$396M
3
FLSM
3
Frazier Life Sciences Management
California
$0
4
RCM
4
RA Capital Management
Massachusetts
$351M
5
Balyasny Asset Management
5
Balyasny Asset Management
Illinois
$3.42M
Name Holding Trade Value Shares
Change 		Shares
Change %
TPWA
226
Twin Peaks Wealth Advisors
California
$482 +$482 +5 New
FLSM
227
Frazier Life Sciences Management
California
– -$36M -678,760 Closed
CAM
228
Cormorant Asset Management
Massachusetts
– -$7.95M -150,000 Closed
Jane Street
229
Jane Street
New York
– -$4.83M -91,118 Closed
Citadel Advisors
230
Citadel Advisors
Florida
– -$3.71M -70,068 Closed
DP
231
Diadema Partners
New Jersey
– -$2.65M -50,000 Closed
AGP
232
Artia Global Partners
Florida
– -$2.65M -50,000 Closed
EI
233
EAM Investors
California
– -$2.39M -45,108 Closed
Walleye Capital
234
Walleye Capital
New York
– -$1.9M -35,828 Closed
BT
235
Banque Transatlantique
France
– -$1.69M -34,598 Closed
XT
236
XTX Topco
Cayman Islands
– -$1.59M -29,949 Closed
CF
237
Corebridge Financial
Texas
– -$1.42M -26,821 Closed
Squarepoint
238
Squarepoint
New York
– -$1.29M -24,413 Closed
FRM
239
Fox Run Management
Connecticut
– -$1.02M -19,172 Closed
JFG
240
Jefferies Financial Group
New York
– -$906K -17,100 Closed
QCM
241
Quantinno Capital Management
New York
– -$905K -17,086 Closed
HSBC Holdings
242
HSBC Holdings
United Kingdom
– -$823K -15,570 Closed
VCM
243
Voleon Capital Management
California
– -$732K -13,819 Closed
American Century Companies
244
American Century Companies
Missouri
– -$704K -13,282 Closed
ETC
245
Exchange Traded Concepts
Oklahoma
– -$631K -11,912 Closed
PAP
246
Persistent Asset Partners
Hong Kong
– -$609K -11,501 Closed
BC
247
Bridgefront Capital
Texas
– -$340K -6,414 Closed
SFAM
248
Springhill Fund Asset Management
Hong Kong
– -$332K -6,277 Closed
FCM
249
Fieldview Capital Management
Michigan
– -$320K -6,037 Closed
BC
250
BIT Capital
Germany
– -$319K -6,013 Closed
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10
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