|
1
|
EcoR1 Capital
San Francisco,
California
|
$559M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$387M
|
+$6.98M
|
+117,524
|
+1%
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$184M
|
+$15.8M
|
+266,245
|
+7%
|
|
|
4
|
|
$171M
|
-$4.16M
|
-70,010
|
-2%
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$103M
|
-$4.13M
|
-69,575
|
-3%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$102M
|
+$14.1M
|
+236,555
|
+13%
|
|
|
7
|
Janus Henderson Group
London,
|
$88.1M
|
+$9.15M
|
+154,078
|
+9%
|
|
|
8
|
Palo Alto Investors
Palo Alto,
California
|
$80M
|
–
|
–
|
–
|
|
|
9
|
First Light Asset Management
Edina,
Minnesota
|
$72.1M
|
-$362K
|
-6,090
|
-0.4%
|
|
|
10
|
Dimensional Fund Advisors
Austin,
Texas
|
$53.2M
|
-$2.81M
|
-47,346
|
-4%
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$49.7M
|
-$589K
|
-9,907
|
-1%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$41.5M
|
+$1.23M
|
+20,639
|
+2%
|
|
|
13
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$41.2M
|
-$1.35M
|
-22,691
|
-3%
|
|
|
14
|
PFM Health Sciences
San Francisco,
California
|
$40.4M
|
+$3.68M
|
+62,025
|
+8%
|
|
|
15
|
Boxer Capital
San Diego,
California
|
$30.2M
|
+$19.3M
|
+325,000
|
+108%
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$29.6M
|
-$8.27M
|
-139,164
|
-18%
|
|
|
17
|
Bank of New York Mellon
New York
|
$24.1M
|
-$882K
|
-14,851
|
-3%
|
|
|
18
|
Eventide Asset Management
Boston,
Massachusetts
|
$21.5M
|
–
|
–
|
–
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$21.1M
|
-$341K
|
-5,746
|
-1%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$19.8M
|
-$126K
|
-2,128
|
-0.5%
|
|
|
21
|
|
$19.4M
|
-$715K
|
-12,034
|
-3%
|
|
|
22
|
Avidity Partners Management
Dallas,
Texas
|
$18.4M
|
-$9.07M
|
-152,695
|
-29%
|
|
|
23
|
Finepoint Capital
Boston,
Massachusetts
|
$16.9M
|
+$1.9M
|
+32,000
|
+10%
|
|
|
24
|
Granahan Investment Management
Waltham,
Massachusetts
|
$16.8M
|
+$3.15M
|
+53,008
|
+18%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$14.9M
|
-$234K
|
-3,946
|
-1%
|
|
