|
1
|
EcoR1 Capital
San Francisco,
California
|
$791M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$540M
|
+$74.2M
|
+1,150,741
|
+17%
|
|
|
3
|
|
$247M
|
-$863K
|
-13,373
|
-0.4%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$243M
|
+$22.7M
|
+351,475
|
+11%
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$151M
|
-$3.54M
|
-54,856
|
-2%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$128M
|
-$14.8M
|
-228,780
|
-11%
|
|
|
7
|
Janus Henderson Group
London,
|
$114M
|
+$4.92M
|
+76,228
|
+5%
|
|
|
8
|
Palo Alto Investors
Palo Alto,
California
|
$113M
|
-$408K
|
-6,319
|
-0.4%
|
|
|
9
|
First Light Asset Management
Edina,
Minnesota
|
$102M
|
-$712K
|
-11,039
|
-0.7%
|
|
|
10
|
Dimensional Fund Advisors
Austin,
Texas
|
$78.5M
|
-$5.32M
|
-82,427
|
-7%
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$71.1M
|
+$6.2M
|
+96,125
|
+10%
|
|
|
12
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$59.8M
|
-$2.48M
|
-38,513
|
-4%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$57.2M
|
+$3.78M
|
+58,597
|
+8%
|
|
|
14
|
PFM Health Sciences
San Francisco,
California
|
$52.9M
|
–
|
–
|
–
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$51.4M
|
–
|
–
|
–
|
|
|
16
|
Avidity Partners Management
Dallas,
Texas
|
$36.5M
|
-$34.4M
|
-533,200
|
-50%
|
|
|
17
|
Bank of New York Mellon
New York
|
$35.1M
|
+$22.6M
|
+350,141
|
+213%
|
|
|
18
|
Eventide Asset Management
Boston,
Massachusetts
|
$30.4M
|
+$414K
|
+6,423
|
+1%
|
|
|
19
|
Nuveen
Charlotte,
North Carolina
|
$30.2M
|
-$4.11M
|
-63,712
|
-13%
|
|
|
20
|
|
$28.3M
|
+$5.57M
|
+86,347
|
+26%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$28.1M
|
+$1.89M
|
+29,287
|
+8%
|
|
|
22
|
Renaissance Technologies
New York
|
$22.1M
|
-$5.39M
|
-83,500
|
-21%
|
|
|
23
|
Finepoint Capital
Boston,
Massachusetts
|
$21.7M
|
-$922K
|
-14,300
|
-4%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$21.3M
|
+$872K
|
+13,512
|
+5%
|
|
|
25
|
Boxer Capital
San Diego,
California
|
$20.5M
|
–
|
–
|
–
|
|
