|
1
|
EcoR1 Capital
San Francisco,
California
|
$557M
|
–
|
–
|
–
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$294M
|
-$6.31M
|
-113,768
|
-2%
|
|
|
3
|
|
$191M
|
+$5.69M
|
+102,596
|
+3%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$131M
|
-$426K
|
-7,690
|
-0.3%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$97.5M
|
+$31.5M
|
+567,706
|
+40%
|
|
|
6
|
Palo Alto Investors
Palo Alto,
California
|
$83.3M
|
–
|
–
|
–
|
|
|
7
|
First Light Asset Management
Edina,
Minnesota
|
$80.2M
|
+$9.62M
|
+173,447
|
+12%
|
|
|
8
|
Dimensional Fund Advisors
Austin,
Texas
|
$74M
|
-$4.5M
|
-81,111
|
-5%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$44.5M
|
+$1.81M
|
+32,726
|
+4%
|
|
|
10
|
Redmile Group
San Francisco,
California
|
$37.8M
|
-$7.53M
|
-135,816
|
-15%
|
|
|
11
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$32M
|
-$3.48M
|
-62,700
|
-9%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$30.8M
|
+$189K
|
+3,401
|
+0.5%
|
|
|
13
|
Nuveen
Charlotte,
North Carolina
|
$24.6M
|
+$1.04M
|
+18,769
|
+4%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$22M
|
+$213K
|
+3,834
|
+0.9%
|
|
|
15
|
Prosight Management
Dallas,
Texas
|
$21.8M
|
+$6.53M
|
+117,700
|
+36%
|
|
|
16
|
Two Sigma Advisers
New York
|
$20.2M
|
-$3.62M
|
-65,300
|
-14%
|
|
|
17
|
Two Sigma Investments
New York
|
$14.9M
|
-$1.09M
|
-19,712
|
-6%
|
|
|
18
|
Boxer Capital
San Diego,
California
|
$14.8M
|
–
|
–
|
–
|
|
|
19
|
Renaissance Technologies
New York
|
$13.2M
|
+$532K
|
+9,600
|
+4%
|
|
|
20
|
|
$12.8M
|
-$1.1M
|
-19,849
|
-7%
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$12.6M
|
+$771K
|
+13,899
|
+6%
|
|
|
22
|
Millennium Management
New York
|
$10.9M
|
+$3.78M
|
+68,222
|
+45%
|
|
|
23
|
|
$10.6M
|
+$11.1M
|
+201,056
|
+1,407%
|
|
|
24
|
Marshall Wace
London,
United Kingdom
|
$10.6M
|
+$8.08M
|
+145,799
|
+212%
|
|
|
25
|
|
$10.6M
|
+$7.66M
|
+138,207
|
+182%
|
|
