|
1
|
EcoR1 Capital
San Francisco,
California
|
$561M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$328M
|
+$149M
|
+2,814,753
|
+71%
|
|
|
3
|
|
$176M
|
+$7.37M
|
+139,559
|
+4%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$155M
|
-$191K
|
-3,610
|
-0.1%
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$110M
|
+$26.5M
|
+501,185
|
+28%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$102M
|
+$2.67M
|
+50,498
|
+2%
|
|
|
7
|
Palo Alto Investors
Palo Alto,
California
|
$80.6M
|
+$275K
|
+5,200
|
+0.3%
|
|
|
8
|
Janus Henderson Group
London,
|
$77.4M
|
+$8.66M
|
+163,980
|
+11%
|
|
|
9
|
First Light Asset Management
Edina,
Minnesota
|
$73.2M
|
-$1.29M
|
-24,431
|
-2%
|
|
|
10
|
Dimensional Fund Advisors
Austin,
Texas
|
$59.7M
|
-$4.64M
|
-87,866
|
-7%
|
|
|
11
|
Avidity Partners Management
Dallas,
Texas
|
$51.8M
|
-$99.6M
|
-1,884,800
|
-64%
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$45.8M
|
+$3.93M
|
+74,422
|
+9%
|
|
|
13
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$44.3M
|
-$701K
|
-13,276
|
-1%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$37.8M
|
+$3.39M
|
+64,223
|
+9%
|
|
|
15
|
PFM Health Sciences
San Francisco,
California
|
$37.5M
|
-$5.33M
|
-100,918
|
-12%
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$36.5M
|
–
|
–
|
–
|
|
|
17
|
Bank of America
Charlotte,
North Carolina
|
$27.4M
|
+$23.4M
|
+442,770
|
+364%
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$24.6M
|
-$3.49M
|
-66,062
|
-12%
|
|
|
19
|
Prosight Management
Dallas,
Texas
|
$21.7M
|
+$6.19M
|
+117,092
|
+35%
|
|
|
20
|
Eventide Asset Management
Boston,
Massachusetts
|
$21.3M
|
–
|
–
|
–
|
|
|
21
|
Renaissance Technologies
New York
|
$19.7M
|
-$3.57M
|
-67,600
|
-14%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$18.5M
|
+$1.11M
|
+21,103
|
+6%
|
|
|
23
|
Two Sigma Advisers
New York
|
$18.5M
|
+$2.87M
|
+54,300
|
+17%
|
|
|
24
|
Two Sigma Investments
New York
|
$17.7M
|
+$8.56M
|
+162,104
|
+80%
|
|
|
25
|
Point72 Asset Management
Stamford,
Connecticut
|
$16.2M
|
+$1.24M
|
+23,493
|
+8%
|
|
