|
1
|
EcoR1 Capital
San Francisco,
California
|
$315M
|
–
|
–
|
–
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$162M
|
-$4.33M
|
-147,954
|
-2%
|
|
|
3
|
|
$94.2M
|
-$11.4M
|
-390,286
|
-10%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$79.4M
|
+$7.31M
|
+249,784
|
+9%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$61M
|
-$3.55M
|
-121,510
|
-5%
|
|
|
6
|
First Light Asset Management
Edina,
Minnesota
|
$52.6M
|
+$2.91M
|
+99,635
|
+5%
|
|
|
7
|
Palo Alto Investors
Palo Alto,
California
|
$45.7M
|
–
|
–
|
–
|
|
|
8
|
Dimensional Fund Advisors
Austin,
Texas
|
$42.5M
|
+$1.8M
|
+61,597
|
+4%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$22.5M
|
-$1.35M
|
-46,224
|
-5%
|
|
|
10
|
Redmile Group
San Francisco,
California
|
$20M
|
–
|
–
|
–
|
|
|
11
|
Nuveen
Charlotte,
North Carolina
|
$19.6M
|
-$23.9K
|
-817
|
-0.1%
|
|
|
12
|
Renaissance Technologies
New York
|
$18.6M
|
+$8.54M
|
+291,800
|
+74%
|
|
|
13
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$18.4M
|
+$437K
|
+14,932
|
+2%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$17.1M
|
-$594K
|
-20,295
|
-3%
|
|
|
15
|
Prosight Management
Dallas,
Texas
|
$14.9M
|
-$484K
|
-16,538
|
-3%
|
|
|
16
|
Finepoint Capital
Boston,
Massachusetts
|
$12.4M
|
+$13.4M
|
+457,500
|
New
|
|
|
17
|
Two Sigma Advisers
New York
|
$12.2M
|
+$922K
|
+31,500
|
+8%
|
|
|
18
|
|
$9.57M
|
+$89.5K
|
+3,061
|
+0.9%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$9.56M
|
-$368K
|
-12,571
|
-3%
|
|
|
20
|
PFM Health Sciences
San Francisco,
California
|
$9.37M
|
+$10.1M
|
+345,114
|
New
|
|
|
21
|
Maple Rock Capital Partners
Toronto,
Ontario, Canada
|
$9.07M
|
–
|
–
|
–
|
|
|
22
|
Boxer Capital
San Diego,
California
|
$8.14M
|
–
|
–
|
–
|
|
|
23
|
|
$7.78M
|
+$1.01M
|
+34,439
|
+14%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$7.53M
|
-$203K
|
-6,927
|
-2%
|
|
|
25
|
|
$7.33M
|
+$340K
|
+11,621
|
+4%
|
|
