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Prothena Corp
PRTA

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$149M +$36.4M +1,128,289 +41%
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$86.4M +$25.7M +798,590 +55%
O
3
OrbiMed
New York
$72.4M +$22.1M +687,000 +57%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$62.3M +$6.67M +206,940 +15%
RCM
5
RA Capital Management
Massachusetts
$59.6M -$2.78M -86,249 -5%
Capital World Investors
6
Capital World Investors
California
$31.7M +$26.6M +826,620 New
Adage Capital Partners
7
Adage Capital Partners
Massachusetts
$31.3M -$4.84M -150,000 -16%
Jennison Associates
8
Jennison Associates
New York
$29.5M -$2.03M -63,121 -8%
Millennium Management
9
Millennium Management
New York
$28.4M +$17.8M +552,318 +293%
BFA
10
BlackRock Fund Advisors
California
$25.5M +$634K +19,656 +3%
RG
11
Redmile Group
California
$21.4M +$17.7M +550,511 +6,050%
PHS
12
PFM Health Sciences
California
$20.8M +$17.5M +541,983 New
PAI
13
Palo Alto Investors
California
$20.4M -$145K -4,500 -0.8%
Westfield Capital Management
14
Westfield Capital Management
Massachusetts
$19.6M -$13.8M -426,850 -45%
CAM
15
Cormorant Asset Management
Massachusetts
$13.4M +$11.3M +350,000 New
PA
16
Perceptive Advisors
New York
$13.4M +$11.3M +350,000 New
GC
17
Guggenheim Capital
Illinois
$10.2M +$446K +13,830 +6%
Norges Bank
18
Norges Bank
Norway
$9.74M -$192K -5,969 -2%
Vanguard Group
19
Vanguard Group
Pennsylvania
$9.3M +$2.4M +74,387 +44%
BBA
20
Baker Bros. Advisors
New York
$8.82M -$3.44M -106,776 -32%
State Street
21
State Street
Massachusetts
$8.37M +$755K +23,421 +12%
Morgan Stanley
22
Morgan Stanley
New York
$7.99M +$6.49M +201,182 +2,713%
Northern Trust
23
Northern Trust
Illinois
$7.34M -$196K -6,068 -3%
BIT
24
BlackRock Institutional Trust
California
$6.65M +$242K +7,504 +5%
CCM
25
Cupps Capital Management
Illinois
$6.29M +$5.29M +164,199 New
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