|
1
|
EcoR1 Capital
San Francisco,
California
|
$702M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$192M
|
+$7.49M
|
+237,020
|
+8%
|
|
|
3
|
|
$190M
|
-$10.5M
|
-332,556
|
-10%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$181M
|
-$94.3M
|
-2,983,847
|
-50%
|
|
|
5
|
Avidity Partners Management
Dallas,
Texas
|
$119M
|
+$62.2M
|
+1,967,000
|
New
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$114M
|
-$11.5M
|
-364,279
|
-16%
|
|
|
7
|
Palo Alto Investors
Palo Alto,
California
|
$100M
|
-$1M
|
-31,700
|
-2%
|
|
|
8
|
First Light Asset Management
Edina,
Minnesota
|
$93.3M
|
-$12.6M
|
-399,505
|
-21%
|
|
|
9
|
Dimensional Fund Advisors
Austin,
Texas
|
$90M
|
-$2.62M
|
-82,848
|
-5%
|
|
|
10
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$51.4M
|
+$26.8M
|
+847,962
|
New
|
|
|
11
|
PFM Health Sciences
San Francisco,
California
|
$50.9M
|
+$15.7M
|
+495,124
|
+143%
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$49M
|
-$668K
|
-21,116
|
-3%
|
|
|
13
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$41.1M
|
–
|
–
|
–
|
|
|
14
|
Renaissance Technologies
New York
|
$38.6M
|
-$1.55M
|
-49,100
|
-7%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$38.5M
|
+$128K
|
+4,044
|
+0.6%
|
|
|
16
|
Redmile Group
San Francisco,
California
|
$31.9M
|
-$6.66M
|
-210,600
|
-29%
|
|
|
17
|
Nuveen
Charlotte,
North Carolina
|
$29.7M
|
-$7.36M
|
-232,720
|
-32%
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$26.2M
|
+$10.7M
|
+338,055
|
+362%
|
|
|
19
|
Maple Rock Capital Partners
Toronto,
Ontario, Canada
|
$24.2M
|
+$2.07M
|
+65,414
|
+20%
|
|
|
20
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$21.2M
|
+$10.9M
|
+345,634
|
+7,676%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$21M
|
-$160K
|
-5,073
|
-1%
|
|
|
22
|
Two Sigma Advisers
New York
|
$20.3M
|
-$3.56M
|
-112,700
|
-25%
|
|
|
23
|
Prosight Management
Dallas,
Texas
|
$19.5M
|
-$7.24M
|
-228,907
|
-42%
|
|
|
24
|
Suvretta Capital Management
New York
|
$19.2M
|
+$10M
|
+316,531
|
New
|
|
|
25
|
Finepoint Capital
Boston,
Massachusetts
|
$18.5M
|
-$4.81M
|
-152,100
|
-33%
|
|
