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Praxis Precision Medicines

289 hedge funds and large institutions have $10.2B invested in Praxis Precision Medicines in 2026 Q1 according to their latest regulatory filings, with 79 funds opening new positions, 121 increasing their positions, 67 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

139% more first-time investments, than exits

New positions opened: 79 | Existing positions closed: 33

81% more repeat investments, than reductions

Existing positions increased: 121 | Existing positions reduced: 67

18% more capital invested

Capital invested by funds: $8.69B → $10.2B (+$1.55B)

16% more funds holding

Funds holding: 250289 (+39)

3.69% less ownership

Funds ownership: 117.84%114.15% (-3.7%)

4% less funds holding in top 10

Funds holding in top 10: 2423 (-1)

71% less call options, than puts

Call options by funds: $53.8M | Put options by funds: $187M

Holders
289
Holders Change
+39
Holders Change %
+15.6%
% of All Funds
3.56%
Holding in Top 10
23
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-4.17%
% of All Funds
0.28%
New
79
Increased
121
Reduced
67
Closed
33
Calls
$53.8M
Puts
$187M
Net Calls
-$133M
Net Calls Change
-$115M
Name Holding Trade Value Shares
Change
Change in
Stake
Fifth Third Bancorp
151
Fifth Third Bancorp
Ohio
$1.16M +$1.11M +3,589 New
AC
152
Allstate Corporation
Illinois
$1.13M +$1.09M +3,512 New
GT
153
Glenmede Trust
Pennsylvania
$1.1M -$890K -2,878 -46%
FC
154
FORA Capital
Florida
$1.1M +$1.06M +3,412 New
QCM
155
Quantinno Capital Management
New York
$1.07M +$185K +597 +22%
HA
156
Homestead Advisers
Virginia
$1.06M +$1.02M +3,300 New
Man Group
157
Man Group
United Kingdom
$1.02M -$5.57M -17,997 -85%
Teacher Retirement System of Texas
158
Teacher Retirement System of Texas
Texas
$987K +$2.78K +9 +0.3%
LPL Financial
159
LPL Financial
California
$942K +$904K +2,923 New
QL
160
Quarry LP
New York
$886K -$387K -1,250 -31%
ACM
161
ACT Capital Management
Pennsylvania
$870K +$619K +2,000 +286%
GC
162
Guggenheim Capital
Illinois
$860K +$826K +2,670 New
AGP
163
Artia Global Partners
Florida
$805K
X
164
Xponance
Pennsylvania
$780K +$203K +656 +37%
Public Employees Retirement Association of Colorado
165
Public Employees Retirement Association of Colorado
Colorado
$770K
AIP
166
Ameritas Investment Partners
Nebraska
$681K +$76.4K +247 +13%
Squarepoint
167
Squarepoint
New York
$648K +$37.1K +120 +6%
EI
168
Ethic Inc
New York
$641K -$62.8K -203 -9%
EFM
169
E Fund Management
China
$630K +$605K +1,956 New
Mercer Global Advisors
170
Mercer Global Advisors
Colorado
$596K +$197K +638 +53%
Amundi
171
Amundi
France
$581K +$313K +1,012 +128%
BG
172
Bellevue Group
Switzerland
$566K +$544K +1,757 New
BCI
173
Brinker Capital Investments
Pennsylvania
$559K -$77.6K -251 -13%
Simplex Trading
174
Simplex Trading
Illinois
$535K +$514K +1,660 New
Hudson Bay Capital Management
175
Hudson Bay Capital Management
Connecticut
$528K +$507K +1,640 New