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Praxis Precision Medicines

250 hedge funds and large institutions have $8.69B invested in Praxis Precision Medicines in 2025 Q4 according to their latest regulatory filings, with 115 funds opening new positions, 87 increasing their positions, 44 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

700% more funds holding in top 10

Funds holding in top 10: 324 (+21)

667% more first-time investments, than exits

New positions opened: 115 | Existing positions closed: 15

564% more capital invested

Capital invested by funds: $1.31B → $8.69B (+$7.38B)

98% more repeat investments, than reductions

Existing positions increased: 87 | Existing positions reduced: 44

64% more funds holding

Funds holding: 152250 (+98)

0.66% more ownership

Funds ownership: 117.18%117.84% (+0.66%)

8% less call options, than puts

Call options by funds: $219M | Put options by funds: $238M

Holders
250
Holders Change
+98
Holders Change %
+64.47%
% of All Funds
3.04%
Holding in Top 10
24
Holding in Top 10 Change
+21
Holding in Top 10 Change %
+700%
% of All Funds
0.29%
New
115
Increased
87
Reduced
44
Closed
15
Calls
$219M
Puts
$238M
Net Calls
-$18.3M
Net Calls Change
-$22.9M
Name Holding Trade Value Shares
Change
Change in
Stake
SO
151
STRS Ohio
Ohio
$943K +$596K +3,200 New
Teacher Retirement System of Texas
152
Teacher Retirement System of Texas
Texas
$900K -$264K -1,416 -32%
QCM
153
Quantinno Capital Management
New York
$803K +$507K +2,723 New
SFCM
154
Seven Fleet Capital Management
California
$796K +$503K +2,700 New
AGP
155
Artia Global Partners
Florida
$737K +$466K +2,500 New
Allianz Asset Management
156
Allianz Asset Management
Germany
$707K +$447K +2,400 New
Public Employees Retirement Association of Colorado
157
Public Employees Retirement Association of Colorado
Colorado
$704K +$405K +2,173 +1,001%
Susquehanna International Group
158
Susquehanna International Group
Pennsylvania
$691K -$5.03M -26,994 -92%
BIG
159
Brooklyn Investment Group
New York
$664K +$406K +2,179 New
EI
160
Ethic Inc
New York
$646K +$408K +2,193 New
AIP
161
Arrowpoint Investment Partners
Singapore
$614K +$388K +2,082 New
QOP
162
Quinn Opportunity Partners
Virginia
$589K +$372K +2,000 New
BCI
163
Brinker Capital Investments
Pennsylvania
$585K +$370K +1,985 New
PR
164
PSP Research
Pennsylvania
$584K +$369K +1,982 New
Squarepoint
165
Squarepoint
New York
$557K +$352K +1,890 New
AIP
166
Ameritas Investment Partners
Nebraska
$550K +$64.6K +347 +23%
YIH
167
Y-Intercept (HK)
Hong Kong
$547K -$5.65M -30,330 -94%
US Bancorp
168
US Bancorp
Minnesota
$538K +$319K +1,713 +1,529%
TCWM
169
Total Clarity Wealth Management
Illinois
$536K +$339K +1,820 New
SG
170
StoneX Group
New York
$521K +$329K +1,766 New
X
171
Xponance
Pennsylvania
$520K +$328K +1,764 New
Allspring Global Investments
172
Allspring Global Investments
North Carolina
$496K +$323K +1,732 New
ACM
173
ADAR1 Capital Management
Texas
$442K +$279K +1,500 New
CWM
174
CIBC World Markets
New York
$439K +$277K +1,490 New
Mackenzie Financial
175
Mackenzie Financial
Ontario, Canada
$415K +$261K +1,399 New