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Praxis Precision Medicines
PRAX

Overview Fund Activity

141 hedge funds and large institutions have $1.01B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 64 increasing their positions, 34 reducing their positions, and 32 closing their positions.

Holders
141
Holders Change
-8
Holders Change %
-5.37%
% of All Funds
1.89%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
64
Reduced
34
Closed
32
Calls
$21.9M
Puts
$11.2M
Net Calls
+$10.7M
Net Calls Change
+$15.7M

Top Buyers

1
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
4
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
5
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
1
VR Adviser
New York
$0
2
Capital Research Global Investors
2
Capital Research Global Investors
California
$0
3
PA
3
Perceptive Advisors
New York
$31.7M
4
SCM
4
Soleus Capital Management
Connecticut
$40.7M
5
SCM
5
Silverarc Capital Management
Massachusetts
$421K
Name Market Value Shares Shares
Change 		Shares
Change %
PWA
151
PCG Wealth Advisors
Kansas
– – -16,413 Closed
Group One Trading
152
Group One Trading
Illinois
– – -10,927 Closed
XT
153
XTX Topco
Cayman Islands
– – -10,043 Closed
CF
154
Corebridge Financial
Texas
– – -8,448 Closed
LP
155
LMR Partners
United Kingdom
– – -7,774 Closed
EGM
156
Engineers Gate Manager
New York
– – -7,606 Closed
YIH
157
Y-Intercept (HK)
Hong Kong
– – -6,250 Closed
SC
158
Shay Capital
New York
– – -5,500 Closed
GCM
159
Graham Capital Management
Connecticut
– – -5,449 Closed
Ameriprise
160
Ameriprise
Minnesota
– – -5,408 Closed
SG Americas Securities
161
SG Americas Securities
New York
– – -3,004 Closed
ACM
162
Aster Capital Management
United Arab Emirates
– – -62 Closed
QT
163
Quantbot Technologies
New York
– – -47 Closed
Comerica Bank
164
Comerica Bank
Texas
– – -40 Closed
SSG
165
Summit Securities Group
New York
– – -40 Closed
CA
166
CoreCap Advisors
Michigan
– – -20 Closed
PWA
167
Physician Wealth Advisors
Utah
– – -17 Closed
CCM
168
Coldstream Capital Management
Washington
– – -13 Closed
TPCW
169
TD Private Client Wealth
New York
– – -11 Closed
SC
170
Stephens Consulting
Michigan
– – -10 Closed
PS
171
Principal Securities
Iowa
– – -6 Closed
CFD
172
Creative Financial Designs
Indiana
– – -6 Closed
Bessemer Group
173
Bessemer Group
New Jersey
– – – –
Nomura Holdings
174
Nomura Holdings
Japan
– – – –
SB
175
SIG Brokerage
New York
– – – –
4 5 6
7
8