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Praxis Precision Medicines
PRAX

Overview Fund Activity

142 hedge funds and large institutions have $1.02B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 65 increasing their positions, 34 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
142
Holders Change
-7
Holders Change %
-4.7%
% of All Funds
1.9%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
65
Reduced
34
Closed
32
Calls
$26.3M
Puts
$15.5M
Net Calls
+$10.8M
Net Calls Change
+$15.8M

Top Buyers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
VR Adviser
New York
$0
2
Capital Research Global Investors
Capital Research Global Investors
California
$0
3
PA
Perceptive Advisors
New York
$31.7M
4
SCM
Soleus Capital Management
Connecticut
$40.7M
5
SCM
Silverarc Capital Management
Massachusetts
$421K
Name Holding Trade Value Shares
Change 		Shares
Change %
BNP Paribas Asset Management
126
BNP Paribas Asset Management
France
$6K +$6K +133 New
A
127
AlphaQuest
New York
$4.88K -$1.35K -32 -22%
SS
128
SBI Securities
Japan
$3.15K +$421 +10 +15%
Daiwa Securities Group
129
Daiwa Securities Group
Japan
$3K – – –
AF
130
Allworth Financial
California
$2.9K +$2.65K +63 +1,050%
RIL
131
Rothschild Investment LLC
Illinois
$2.1K +$1.89K +45 +900%
IA
132
IFP Advisors
Florida
$1.89K -$38 -1 Closed
LFG
133
Larson Financial Group
Missouri
$1.6K +$1.6K +38 New
PNC Financial Services Group
134
PNC Financial Services Group
Pennsylvania
$1.01K +$799 +19 +380%
HWM
135
Hemington Wealth Management
Virginia
$1K – – –
AAP
136
Arax Advisory Partners
Colorado
$968 +$968 +23 New
Osaic Holdings
137
Osaic Holdings
Arizona
$883 -$1.89K -45 -68%
FWM
138
FSA Wealth Management
Massachusetts
$883 – – –
EWA
139
EverSource Wealth Advisors
Alabama
$757 +$294 +7 +64%
PFBT
140
Parkside Financial Bank & Trust
Missouri
$421 – – –
TPWA
141
Twin Peaks Wealth Advisors
California
$48 +$48 +1 New
National Bank of Canada
142
National Bank of Canada
Quebec, Canada
$42 +$42 +1 New
VA
143
VR Adviser
New York
– -$37.5M -989,985 Closed
Capital Research Global Investors
144
Capital Research Global Investors
California
– -$32.3M -853,746 Closed
Walleye Capital
145
Walleye Capital
New York
– -$4.99M -131,756 Closed
SCM
146
Sio Capital Management
New York
– -$4.26M -112,500 Closed
FTM
147
First Turn Management
California
– -$2.72M -71,775 Closed
Millennium Management
148
Millennium Management
New York
– -$2.62M -69,181 Closed
ECM
149
ExodusPoint Capital Management
New York
– -$1.51M -39,975 Closed
MAP
150
Moody Aldrich Partners
Massachusetts
– -$1.14M -30,221 Closed
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