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Praxis Precision Medicines
PRAX

Overview Fund Activity

142 hedge funds and large institutions have $1.02B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 65 increasing their positions, 34 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
142
Holders Change
-7
Holders Change %
-4.7%
% of All Funds
1.9%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
65
Reduced
34
Closed
32
Calls
$26.3M
Puts
$15.5M
Net Calls
+$10.8M
Net Calls Change
+$15.8M

Top Buyers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
VR Adviser
New York
$0
2
Capital Research Global Investors
Capital Research Global Investors
California
$0
3
PA
Perceptive Advisors
New York
$31.7M
4
SCM
Soleus Capital Management
Connecticut
$40.7M
5
SCM
Silverarc Capital Management
Massachusetts
$421K
Name Holding Trade Value Shares
Change 		Shares
Change %
Bank of New York Mellon
51
Bank of New York Mellon
New York
$2.21M +$263K +6,246 +13%
Susquehanna International Group
52
Susquehanna International Group
Pennsylvania
$1.97M +$512K +12,179 +35%
WP
53
Woodline Partners
California
$1.93M -$5.46M -129,775 -74%
Jacobs Levy Equity Management
54
Jacobs Levy Equity Management
New Jersey
$1.9M +$214K +5,083 +13%
CM
55
Caption Management
Oklahoma
$1.64M +$873K +20,756 +114%
NL
56
Nuveen LLC
North Carolina
$1.62M +$1M +23,787 +161%
Fidelity Investments
57
Fidelity Investments
Massachusetts
$1.6M +$100K +2,381 +7%
BGI
58
B Group Inc
Texas
$1.47M +$673K +16,000 +84%
SC
59
Stempoint Capital
New York
$1.36M +$1.36M +32,255 New
Swiss National Bank
60
Swiss National Bank
Switzerland
$1.3M +$156K +3,700 +14%
AG
61
Algert Global
California
$1.16M +$256K +6,080 +28%
RhumbLine Advisers
62
RhumbLine Advisers
Massachusetts
$1.15M +$128K +3,047 +13%
Simplex Trading
63
Simplex Trading
Illinois
$1.07M +$926K +22,030 +668%
Rafferty Asset Management
64
Rafferty Asset Management
New York
$1.04M -$187K -4,440 -15%
Capital Fund Management (CFM)
65
Capital Fund Management (CFM)
France
$1.02M +$1.02M +24,292 New
Mirae Asset Global ETFs Holdings
66
Mirae Asset Global ETFs Holdings
Hong Kong
$1.01M +$512K +12,165 +104%
Royal Bank of Canada
67
Royal Bank of Canada
Ontario, Canada
$950K +$945K +22,485 +20,819%
UOC
68
UBS O'Connor
Illinois
$921K -$206K -4,901 -18%
PCM
69
Prelude Capital Management
New York
$837K +$837K +19,900 New
D.E. Shaw & Co
70
D.E. Shaw & Co
New York
$801K +$288K +6,848 +56%
AllianceBernstein
71
AllianceBernstein
Tennessee
$759K -$1.39M -33,076 -65%
Legal & General Group
72
Legal & General Group
United Kingdom
$701K +$95.1K +2,261 +16%
California State Teachers Retirement System (CalSTRS)
73
California State Teachers Retirement System (CalSTRS)
California
$687K – – –
Invesco
74
Invesco
Georgia
$670K +$179K +4,261 +36%
SI
75
Sofinnova Investments
California
$661K -$5.97M -141,923 -90%
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