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Praxis Precision Medicines

289 hedge funds and large institutions have $10.2B invested in Praxis Precision Medicines in 2026 Q1 according to their latest regulatory filings, with 79 funds opening new positions, 121 increasing their positions, 67 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

139% more first-time investments, than exits

New positions opened: 79 | Existing positions closed: 33

81% more repeat investments, than reductions

Existing positions increased: 121 | Existing positions reduced: 67

18% more capital invested

Capital invested by funds: $8.69B → $10.2B (+$1.55B)

16% more funds holding

Funds holding: 250289 (+39)

3.69% less ownership

Funds ownership: 117.84%114.15% (-3.7%)

4% less funds holding in top 10

Funds holding in top 10: 2423 (-1)

71% less call options, than puts

Call options by funds: $53.8M | Put options by funds: $187M

Holders
289
Holders Change
+39
Holders Change %
+15.6%
% of All Funds
3.56%
Holding in Top 10
23
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-4.17%
% of All Funds
0.28%
New
79
Increased
121
Reduced
67
Closed
33
Calls
$53.8M
Puts
$187M
Net Calls
-$133M
Net Calls Change
-$115M
Name Holding Trade Value Shares
Change
Change in
Stake
Northern Trust
26
Northern Trust
Illinois
$73.4M +$11M +35,650 +19%
Charles Schwab
27
Charles Schwab
California
$69.4M +$5.3M +17,146 +9%
WP
28
Woodline Partners
California
$64.4M +$29.3M +94,601 +90%
T. Rowe Price Investment Management
29
T. Rowe Price Investment Management
Maryland
$56.5M -$31.3M -101,155 -37%
Wellington Management Group
30
Wellington Management Group
Massachusetts
$56.2M -$684K -2,212 -1%
O
31
OrbiMed
New York
$55.6M +$24.1M +78,000 +83%
Aberdeen Group
32
Aberdeen Group
United Kingdom
$55.6M +$11.6M +37,492 +28%
AAA
33
Affinity Asset Advisors
New York
$54.8M -$4.64M -15,000 -8%
VFT
34
Vanguard Fiduciary Trust
Pennsylvania
$54.7M +$52.6M +169,902 New
BNP Paribas Financial Markets
35
BNP Paribas Financial Markets
France
$46.1M +$42.8M +138,456 +2,993%
American Century Companies
36
American Century Companies
Missouri
$41.3M +$16.4M +52,888 +70%
Qube Research & Technologies (QRT)
37
Qube Research & Technologies (QRT)
United Kingdom
$41.3M -$12.6M -40,669 -24%
ACH
38
ArrowMark Colorado Holdings
Colorado
$38M +$27.2M +87,851 +293%
UBS Group
39
UBS Group
Switzerland
$34.9M +$5.95M +19,246 +22%
VCIM
40
Velan Capital Investment Management
Georgia
$32.5M
Bank of New York Mellon
41
Bank of New York Mellon
New York
$28M +$2.83M +9,150 +12%
ACP
42
Acuta Capital Partners
California
$27.4M +$577K +1,865 +2%
MIM
43
MetLife Investment Management
New Jersey
$26.1M +$21.2M +68,506 +551%
Alyeska Investment Group
44
Alyeska Investment Group
Illinois
$23.3M -$680K -2,198 -3%
N
45
Nuveen
North Carolina
$23.2M +$6.83M +22,073 +44%
IC
46
Ikarian Capital
Texas
$23.1M -$4.64M -15,000 -17%
SCM
47
Silverarc Capital Management
Massachusetts
$23.1M -$3.38M -10,913 -13%
JP Morgan Chase
48
JP Morgan Chase
New York
$22.2M +$7.7M +24,880 +45%
Ensign Peak Advisors
49
Ensign Peak Advisors
Utah
$22M +$1.27M +4,100 +6%
7IH
50
72 Investment Holdings
Connecticut
$21.2M