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Praxis Precision Medicines
PRAX

100 hedge funds and large institutions have $863M invested in Praxis Precision Medicines in 2021 Q4 according to their latest regulatory filings, with 16 funds opening new positions, 45 increasing their positions, 16 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

181% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 16

129% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 7

9% more capital invested

Capital invested by funds: $792M → $863M (+$71.3M)

9% more funds holding

Funds holding: 92 → 100 (+8)

0.13% more ownership

Funds ownership: 6.38% → 6.51% (+0.13%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

Holders
100
Holders Change
+8
Holders Change %
+8.7%
% of All Funds
1.54%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
16
Increased
45
Reduced
16
Closed
7
Calls
$572K
Puts
–
Net Calls
+$572K
Net Calls Change
+$166K

Top Buyers

1
State Street
State Street
Massachusetts
+$14.9M
2
BlackRock
BlackRock
New York
+$6.88M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$6.05M
4
AllianceBernstein
AllianceBernstein
Tennessee
+$4.47M
5
PHS
PFM Health Sciences
California
+$3.53M

Top Sellers

1
Blackstone Inc
Blackstone Inc
New York
-$8.73M
2
CAM
Cormorant Asset Management
Massachusetts
-$5.31M
3
GTC
Ghost Tree Capital
New York
-$4.62M
4
Verition Fund Management
Verition Fund Management
Connecticut
-$3.91M
5
Marshall Wace
Marshall Wace
United Kingdom
-$3.62M
Name Holding Trade Value Shares
Change 		Change in
Stake
Charles Schwab
26
Charles Schwab
California
$4.88M +$192K +656 +4%
N
27
Nuveen
North Carolina
$4.31M +$1.83M +6,226 +75%
Verition Fund Management
28
Verition Fund Management
Connecticut
$4.18M -$3.91M -13,333 -49%
Jennison Associates
29
Jennison Associates
New York
$3.82M -$31.1K -106 -0.8%
Two Sigma Investments
30
Two Sigma Investments
New York
$3M +$499K +1,703 +20%
RJA
31
Raymond James & Associates
Florida
$2.33M – – –
Bank of New York Mellon
32
Bank of New York Mellon
New York
$2.12M +$78K +266 +4%
Bank of America
33
Bank of America
North Carolina
$1.82M +$1.32M +4,488 +269%
ECM
34
Endurant Capital Management
California
$1.76M -$1.25M -4,269 -42%
UBS Group
35
UBS Group
Switzerland
$1.7M +$1.68M +5,736 +143,400%
Citigroup
36
Citigroup
New York
$1.59M +$832K +2,837 +112%
Goldman Sachs
37
Goldman Sachs
New York
$1.5M -$645K -2,200 -30%
TCM
38
Tekla Capital Management
Massachusetts
$1.48M – – –
Rafferty Asset Management
39
Rafferty Asset Management
New York
$1.33M +$1.32M +4,499 New
Two Sigma Advisers
40
Two Sigma Advisers
New York
$1.23M +$637K +2,173 +109%
AA
41
ALPS Advisors
Colorado
$1.02M -$61.6K -210 -6%
Swiss National Bank
42
Swiss National Bank
Switzerland
$969K +$23.5K +80 +3%
RhumbLine Advisers
43
RhumbLine Advisers
Massachusetts
$747K +$44.3K +151 +6%
California State Teachers Retirement System (CalSTRS)
44
California State Teachers Retirement System (CalSTRS)
California
$730K +$33.7K +115 +5%
VFA
45
Values First Advisors
Tennessee
$701K +$178K +606 +34%
Millennium Management
46
Millennium Management
New York
$674K -$1.52M -5,183 -69%
State of Wisconsin Investment Board
47
State of Wisconsin Investment Board
Wisconsin
$621K – – –
AWA
48
Alta Wealth Advisors
Massachusetts
$611K – – –
JP Morgan Chase
49
JP Morgan Chase
New York
$568K +$112K +383 +25%
T. Rowe Price Associates
50
T. Rowe Price Associates
Maryland
$527K +$117K +398 +29%
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PRAX Hedge Fund Activity: Q4 2021 in Review

100 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Praxis Precision Medicines (PRAX) for Q4 2021, worth a combined $863M — up 9% from $792M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new PRAX positions and 7 closed out — a net gain of 9 holders — while 45 added to existing stakes and 16 trimmed.

The largest buyer was State Street, adding an estimated $14.9M. The largest seller was Blackstone Inc, cutting an estimated $8.73M.

  • 100 institutional investors held Praxis Precision Medicines (PRAX) as of Q4 2021, up from 92 in Q3 2021.
  • Funds reported $863M of Praxis Precision Medicines stock for Q4 2021, up 9% quarter-over-quarter.
  • 16 funds opened new Praxis Precision Medicines positions in Q4 2021 and 7 closed out, a net change of +9 holders.
  • The largest Praxis Precision Medicines buyer in Q4 2021 was State Street, an estimated $14.9M added.
  • The largest Praxis Precision Medicines seller in Q4 2021 was Blackstone Inc, an estimated $8.73M sold.

Based on aggregated 13F filings for Q4 2021.