We are live on ! Find out more
PLRX icon

Pliant Therapeutics
PLRX

91 hedge funds and large institutions have $62.5M invested in Pliant Therapeutics in 2026 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 26 increasing their positions, 26 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

9% more capital invested

Capital invested by funds: $57.5M → $62.5M (+$4.94M)

4.26% more ownership

Funds ownership: 75.98% → 80.24% (+4.3%)

0% more repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 26

6% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 16

5% less funds holding

Funds holding: 96 → 91 (-5)

63% less call options, than puts

Call options by funds: $89K | Put options by funds: $238K

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders
91
Holders Change
-5
Holders Change %
-5.21%
% of All Funds
1.12%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
15
Increased
26
Reduced
26
Closed
16
Calls
$89K
Puts
$238K
Net Calls
-$149K
Net Calls Change
-$133K

Top Buyers

1
ACM
ADAR1 Capital Management
Texas
+$3.17M
2
Two Sigma Investments
Two Sigma Investments
New York
+$1.64M
3
Renaissance Technologies
Renaissance Technologies
New York
+$1.02M
4
Millennium Management
Millennium Management
New York
+$974K
5
Citadel Advisors
Citadel Advisors
Florida
+$812K

Top Sellers

1
RG
Redmile Group
California
-$1.07M
2
CC
Centiva Capital
New York
-$716K
3
DekaBank Deutsche Girozentrale
DekaBank Deutsche Girozentrale
Germany
-$633K
4
WP
Woodline Partners
California
-$454K
5
Bank of America
Bank of America
North Carolina
-$453K
Name Holding Trade Value Shares
Change 		Change in
Stake
Rockefeller Capital Management
76
Rockefeller Capital Management
New York
$832 – – –
BNP Paribas Financial Markets
77
BNP Paribas Financial Markets
France
$828 – – –
Fidelity Investments
78
Fidelity Investments
Massachusetts
$660 -$1.78K -1,410 -73%
HI
79
Harbour Investments
Wisconsin
$615 +$616 +488 New
MCM
80
MAI Capital Management
Ohio
$504 – – –
SS
81
SBI Securities
Japan
$378 -$25 -20 -6%
Carson Wealth (CWM LLC)
82
Carson Wealth (CWM LLC)
Nebraska
$267 -$226 -179 -46%
Northwestern Mutual Wealth Management
83
Northwestern Mutual Wealth Management
Wisconsin
$126 +$126 +100 New
TC
84
Truvestments Capital
Florida
$63 – – –
Wells Fargo
85
Wells Fargo
California
$63 – – –
Zurich Cantonal Bank
86
Zurich Cantonal Bank
Switzerland
$45 +$45 +36 New
Barclays
87
Barclays
United Kingdom
$43 -$13.3K -10,550 -100%
FFA
88
Farther Finance Advisors
California
$7 – – –
CIAM
89
Caitong International Asset Management
Hong Kong
$5 +$4 +3 +300%
Fifth Third Bancorp
90
Fifth Third Bancorp
Ohio
$5 +$5 +4 New
Two Sigma Advisers
91
Two Sigma Advisers
New York
– -$1.52M -1,245,600 Closed
SFCM
92
Seven Fleet Capital Management
California
– -$337K -276,500 Closed
RHJA
93
Rice Hall James & Associates
California
– -$180K -147,705 Closed
DP
94
Diadema Partners
New Jersey
– -$177K -144,914 Closed
Canada Pension Plan Investment Board
95
Canada Pension Plan Investment Board
Ontario, Canada
– -$74.9K -61,400 Closed
DekaBank Deutsche Girozentrale
96
DekaBank Deutsche Girozentrale
Germany
– -$633K -40,000 Closed
PAP
97
Persistent Asset Partners
Hong Kong
– -$47.4K -38,831 Closed
EGM
98
Engineers Gate Manager
New York
– -$37.3K -30,544 Closed
Group One Trading
99
Group One Trading
Illinois
– -$19.9K -15,790 Closed
A
100
AlphaQuest
New York
– -$14.3K -11,716 Closed
1 2 3
4
5

PLRX Hedge Fund Activity: Q1 2026 in Review

91 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Pliant Therapeutics (PLRX) for Q1 2026, worth a combined $62.5M — up 8.6% from $57.5M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of PLRX and 15 opened new positions — a net loss of 1 holder — while 26 trimmed existing stakes and 26 added.

The largest buyer was ADAR1 Capital Management, adding an estimated $3.17M. The largest seller was Redmile Group, cutting an estimated $1.07M.

  • 91 institutional investors held Pliant Therapeutics (PLRX) as of Q1 2026, down from 96 in Q4 2025.
  • Funds reported $62.5M of Pliant Therapeutics stock for Q1 2026, up 8.6% quarter-over-quarter.
  • 15 funds opened new Pliant Therapeutics positions in Q1 2026 and 16 closed out, a net change of -1 holder.
  • The largest Pliant Therapeutics buyer in Q1 2026 was ADAR1 Capital Management, an estimated $3.17M added.
  • The largest Pliant Therapeutics seller in Q1 2026 was Redmile Group, an estimated $1.07M sold.

Based on aggregated 13F filings for Q1 2026.