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Pliant Therapeutics
PLRX

91 hedge funds and large institutions have $62.5M invested in Pliant Therapeutics in 2026 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 26 increasing their positions, 26 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

9% more capital invested

Capital invested by funds: $57.5M → $62.5M (+$4.94M)

4.26% more ownership

Funds ownership: 75.98% → 80.24% (+4.3%)

0% more repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 26

6% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 16

5% less funds holding

Funds holding: 96 → 91 (-5)

63% less call options, than puts

Call options by funds: $89K | Put options by funds: $238K

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders
91
Holders Change
-5
Holders Change %
-5.21%
% of All Funds
1.12%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
15
Increased
26
Reduced
26
Closed
16
Calls
$89K
Puts
$238K
Net Calls
-$149K
Net Calls Change
-$133K

Top Buyers

1
ACM
ADAR1 Capital Management
Texas
+$3.17M
2
Two Sigma Investments
Two Sigma Investments
New York
+$1.64M
3
Renaissance Technologies
Renaissance Technologies
New York
+$1.02M
4
Millennium Management
Millennium Management
New York
+$974K
5
Citadel Advisors
Citadel Advisors
Florida
+$812K

Top Sellers

1
RG
Redmile Group
California
-$1.07M
2
CC
Centiva Capital
New York
-$716K
3
DekaBank Deutsche Girozentrale
DekaBank Deutsche Girozentrale
Germany
-$633K
4
WP
Woodline Partners
California
-$454K
5
Bank of America
Bank of America
North Carolina
-$453K
Name Holding Trade Value Shares
Change 		Change in
Stake
TCM
1
Tang Capital Management
California
$7.74M – – –
Citadel Advisors
2
Citadel Advisors
Florida
$4.07M +$812K +643,267 +25%
BOCH
3
Blue Owl Capital Holdings
New York
$3.74M – – –
ACM
4
ADAR1 Capital Management
Texas
$3.26M +$3.17M +2,511,307 +3,402%
Acadian Asset Management
5
Acadian Asset Management
Massachusetts
$3.04M +$65.4K +51,839 +2%
VCM
6
Vanguard Capital Management
Pennsylvania
$2.95M +$2.96M +2,343,101 New
Two Sigma Investments
7
Two Sigma Investments
New York
$2.84M +$1.64M +1,299,845 +136%
MAM
8
Monaco Asset Management
Monaco
$2.44M – – –
Renaissance Technologies
9
Renaissance Technologies
New York
$2.33M +$1.02M +807,024 +77%
PM
10
Prosight Management
Texas
$2.1M +$141K +111,856 +7%
WP
11
Woodline Partners
California
$2.1M -$454K -359,361 -18%
BCM
12
BML Capital Management
Indiana
$1.95M – – –
PLC
13
Peapod Lane Capital
New York
$1.59M +$508K +402,204 +45%
Millennium Management
14
Millennium Management
New York
$1.49M +$974K +771,687 +189%
BlackRock
15
BlackRock
New York
$1.38M +$29.2K +23,158 +2%
UBS Group
16
UBS Group
Switzerland
$1.33M -$5.88K -4,661 -0.4%
Marshall Wace
17
Marshall Wace
United Kingdom
$1.25M -$106K -84,155 -8%
EP
18
Eversept Partners
New York
$1.12M +$62.4K +49,402 +6%
JP Morgan Chase
19
JP Morgan Chase
New York
$1.01M -$443K -351,052 -29%
RG
20
Redmile Group
California
$973K -$1.07M -844,102 -52%
Jacobs Levy Equity Management
21
Jacobs Levy Equity Management
New Jersey
$905K +$204K +161,605 +29%
Goldman Sachs
22
Goldman Sachs
New York
$752K +$404K +319,971 +116%
BCM
23
Bridgeway Capital Management
Texas
$698K +$293K +232,100 +72%
Bessemer Group
24
Bessemer Group
New Jersey
$670K – – –
Connor, Clark & Lunn Investment Management (CC&L)
25
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$652K +$184K +145,502 +39%
1
2 3 4 5

PLRX Hedge Fund Activity: Q1 2026 in Review

91 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Pliant Therapeutics (PLRX) for Q1 2026, worth a combined $62.5M — up 8.6% from $57.5M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of PLRX and 15 opened new positions — a net loss of 1 holder — while 26 trimmed existing stakes and 26 added.

The largest buyer was ADAR1 Capital Management, adding an estimated $3.17M. The largest seller was Redmile Group, cutting an estimated $1.07M.

  • 91 institutional investors held Pliant Therapeutics (PLRX) as of Q1 2026, down from 96 in Q4 2025.
  • Funds reported $62.5M of Pliant Therapeutics stock for Q1 2026, up 8.6% quarter-over-quarter.
  • 15 funds opened new Pliant Therapeutics positions in Q1 2026 and 16 closed out, a net change of -1 holder.
  • The largest Pliant Therapeutics buyer in Q1 2026 was ADAR1 Capital Management, an estimated $3.17M added.
  • The largest Pliant Therapeutics seller in Q1 2026 was Redmile Group, an estimated $1.07M sold.

Based on aggregated 13F filings for Q1 2026.