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Pliant Therapeutics

114 hedge funds and large institutions have $59.7M invested in Pliant Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 30 increasing their positions, 39 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

22% more call options, than puts

Call options by funds: $133K | Put options by funds: $109K

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

10.65% less ownership

Funds ownership: 94.53%83.88% (-11%)

19% less funds holding

Funds holding: 140114 (-26)

23% less repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 39

24% less capital invested

Capital invested by funds: $78.5M → $59.7M (-$18.8M)

52% less first-time investments, than exits

New positions opened: 24 | Existing positions closed: 50

Holders
114
Holders Change
-26
Holders Change %
-18.57%
% of All Funds
1.5%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
24
Increased
30
Reduced
39
Closed
50
Calls
$133K
Puts
$109K
Net Calls
+$24K
Net Calls Change
-$180K
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
1
Tang Capital Management
California
$6.96M
DTC
2
Deep Track Capital
Connecticut
$4.58M -$2.05M -1,451,874 -27%
Morgan Stanley
3
Morgan Stanley
New York
$4.35M +$992K +702,099 +23%
Vanguard Group
4
Vanguard Group
Pennsylvania
$3.48M -$469K -332,227 -10%
BOCH
5
Blue Owl Capital Holdings
New York
$3.44M
UBS Group
6
UBS Group
Switzerland
$3.07M +$1.43K +1,010 +0%
Citadel Advisors
7
Citadel Advisors
Florida
$2.73M +$3.33M +2,355,834 +3,624,360%
WP
8
Woodline Partners
California
$2.72M -$234K -165,558 -7%
MAP
9
Madison Avenue Partners
New York
$2.59M +$784K +554,969 +33%
TGI
10
TRV GP IV
Massachusetts
$2.47M
BlackRock
11
BlackRock
New York
$2.47M -$4.4M -3,111,240 -59%
JP Morgan Chase
12
JP Morgan Chase
New York
$2.27M +$2.09M +1,477,336 +307%
RG
13
Redmile Group
California
$1.89M -$595K -420,982 -21%
Acadian Asset Management
14
Acadian Asset Management
Massachusetts
$1.88M +$579K +409,967 +34%
PLC
15
Peapod Lane Capital
New York
$1.04M +$355K +251,537 +39%
Millennium Management
16
Millennium Management
New York
$987K +$1.2M +850,474 New
GPP
17
Great Point Partners
Connecticut
$986K
PM
18
Prosight Management
Texas
$971K +$711K +503,137 +151%
MAM
19
Monaco Asset Management
Monaco
$815K +$992K +702,393 New
Goldman Sachs
20
Goldman Sachs
New York
$692K +$171K +120,821 +25%
Geode Capital Management
21
Geode Capital Management
Massachusetts
$676K -$1.09M -770,457 -57%
Bessemer Group
22
Bessemer Group
New Jersey
$618K
Bank of America
23
Bank of America
North Carolina
$557K -$622K -440,206 -48%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$528K +$160K +113,000 +33%
XT
25
XTX Topco
Cayman Islands
$498K -$53.5K -37,832 -8%

PLRX Hedge Fund Activity: Q2 2025 in Review

114 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Pliant Therapeutics (PLRX) for Q2 2025, worth a combined $59.7M — down 24% from $78.5M a quarter earlier.

Sellers outnumbered buyers: 50 funds closed out of PLRX and 24 opened new positions — a net loss of 26 holders — while 39 trimmed existing stakes and 30 added.

The largest buyer was Citadel Advisors, adding an estimated $3.33M. The largest seller was BlackRock, cutting an estimated $4.4M.

  • 114 institutional investors held Pliant Therapeutics (PLRX) as of Q2 2025, down from 140 in Q1 2025.
  • Funds reported $59.7M of Pliant Therapeutics stock for Q2 2025, down 24% quarter-over-quarter.
  • 24 funds opened new Pliant Therapeutics positions in Q2 2025 and 50 closed out, a net change of -26 holders.
  • The largest Pliant Therapeutics buyer in Q2 2025 was Citadel Advisors, an estimated $3.33M added.
  • The largest Pliant Therapeutics seller in Q2 2025 was BlackRock, an estimated $4.4M sold.

Based on aggregated 13F filings for Q2 2025.