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Pliant Therapeutics

91 hedge funds and large institutions have $62.5M invested in Pliant Therapeutics in 2026 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 26 increasing their positions, 26 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

9% more capital invested

Capital invested by funds: $57.5M → $62.5M (+$4.94M)

4.26% more ownership

Funds ownership: 75.98%80.24% (+4.3%)

0% more repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 26

6% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 16

5% less funds holding

Funds holding: 9691 (-5)

63% less call options, than puts

Call options by funds: $89K | Put options by funds: $238K

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
91
Holders Change
-5
Holders Change %
-5.21%
% of All Funds
1.12%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
15
Increased
26
Reduced
26
Closed
16
Calls
$89K
Puts
$238K
Net Calls
-$149K
Net Calls Change
-$133K
Name Holding Trade Value Shares
Change
Change in
Stake
Dimensional Fund Advisors
51
Dimensional Fund Advisors
Texas
$125K -$27.8K -21,983 -18%
VA
52
Verdad Advisers
Massachusetts
$124K +$124K +98,320 New
AG
53
Algert Global
California
$106K
Federated Hermes
54
Federated Hermes
Pennsylvania
$78.9K +$3.98K +3,156 +5%
Ameriprise
55
Ameriprise
Minnesota
$69.5K +$69.6K +55,129 New
Susquehanna International Group
56
Susquehanna International Group
Pennsylvania
$66.7K +$23.7K +18,755 +55%
QC
57
Quadrature Capital
United Kingdom
$64.2K -$59.2K -46,910 -48%
Simplex Trading
58
Simplex Trading
Illinois
$60.5K +$2.7K +2,142 +5%
Point72 Asset Management
59
Point72 Asset Management
Connecticut
$59.3K +$653 +517 +1%
Tudor Investment Corp
60
Tudor Investment Corp
Connecticut
$37.5K
Ohio Public Employees Retirement System (OPERS)
61
Ohio Public Employees Retirement System (OPERS)
Ohio
$35.9K +$36K +28,500 New
Blackstone Inc
62
Blackstone Inc
New York
$28K
VGA
63
Vanguard Global Advisers
Pennsylvania
$24.6K +$24.6K +19,507 New
BCM
64
Bronte Capital Management
Australia
$23.5K
Universal-Beteiligungs- und Servicegesellschaft
65
Universal-Beteiligungs- und Servicegesellschaft
Germany
$22.8K
Bank of New York Mellon
66
Bank of New York Mellon
New York
$19.9K
SG Americas Securities
67
SG Americas Securities
New York
$16K +$433 +343 +3%
FT
68
Fiduciary Trust
Massachusetts
$14.6K
HF
69
HRT Financial
New York
$14K -$26.5K -21,009 -65%
Qube Research & Technologies (QRT)
70
Qube Research & Technologies (QRT)
United Kingdom
$13.8K -$5.63K -4,459 -29%
VPIM
71
Vanguard Personalized Indexing Management
California
$12.6K -$20.5K -16,208 -62%
TRCT
72
Tower Research Capital (TRC)
New York
$4.18K +$4.18K +3,315 New
RhumbLine Advisers
73
RhumbLine Advisers
Massachusetts
$3K
OCWP
74
Owl Creek Wealth Partners
Colorado
$2.9K +$2.9K +2,300 New
Royal Bank of Canada
75
Royal Bank of Canada
Ontario, Canada
$2K -$237 -188 -16%

PLRX Hedge Fund Activity: Q1 2026 in Review

91 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Pliant Therapeutics (PLRX) for Q1 2026, worth a combined $62.5M — up 8.6% from $57.5M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of PLRX and 15 opened new positions — a net loss of 1 holder — while 26 trimmed existing stakes and 26 added.

The largest buyer was ADAR1 Capital Management, adding an estimated $3.17M. The largest seller was Redmile Group, cutting an estimated $1.07M.

  • 91 institutional investors held Pliant Therapeutics (PLRX) as of Q1 2026, down from 96 in Q4 2025.
  • Funds reported $62.5M of Pliant Therapeutics stock for Q1 2026, up 8.6% quarter-over-quarter.
  • 15 funds opened new Pliant Therapeutics positions in Q1 2026 and 16 closed out, a net change of -1 holder.
  • The largest Pliant Therapeutics buyer in Q1 2026 was ADAR1 Capital Management, an estimated $3.17M added.
  • The largest Pliant Therapeutics seller in Q1 2026 was Redmile Group, an estimated $1.07M sold.

Based on aggregated 13F filings for Q1 2026.