Pliant Therapeutics
PLRX
91 hedge funds and large institutions have $62.5M invested in Pliant Therapeutics in 2026 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 26 increasing their positions, 26 reducing their positions, and 16 closing their positions.
9% more capital invested
Capital invested by funds: $57.5M → $62.5M (+$4.94M)
4.26% more ownership
Funds ownership: 75.98% → 80.24% (+4.3%)
0% more repeat investments, than reductions
Existing positions increased: 26 | Existing positions reduced: 26
6% less first-time investments, than exits
New positions opened: 15 | Existing positions closed: 16
5% less funds holding
Funds holding: 96 → 91 (-5)
63% less call options, than puts
Call options by funds: $89K | Put options by funds: $238K
100% less funds holding in top 10
Funds holding in top 10: 1 → 0 (-1)
Top Buyers
| 1 |
ACM
ADAR1 Capital Management
Austin,
Texas
|
+$3.17M |
| 2 |
Two Sigma Investments
New York
|
+$1.64M |
| 3 |
Renaissance Technologies
New York
|
+$1.02M |
| 4 |
Millennium Management
New York
|
+$974K |
| 5 |
Citadel Advisors
Miami,
Florida
|
+$812K |
Top Sellers
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
FFO
101
Fortitude Family Office
Scottsdale,
Arizona
| – | -$1.56K | -1,278 | Closed |
|
102
PNC Financial Services Group
Pittsburgh,
Pennsylvania
| – | -$1.19K | -978 | Closed |
|
103
Russell Investments Group
London,
United Kingdom
| – | -$661 | -542 | Closed |
|
|
BFS
104
Bare Financial Services
Gap,
Pennsylvania
| – | -$504 | -413 | Closed |
|
|
CFM
105
Cornerstone Financial Management
Burlington,
Massachusetts
| – | -$389 | -319 | Closed |
|
|
CAL
106
Capital Advisors Ltd
Shaker Heights,
Ohio
| – | +$25 | +20 | New |
|
PLRX Hedge Fund Activity: Q1 2026 in Review
91 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Pliant Therapeutics (PLRX) for Q1 2026, worth a combined $62.5M — up 8.6% from $57.5M a quarter earlier.
Sellers outnumbered buyers: 16 funds closed out of PLRX and 15 opened new positions — a net loss of 1 holder — while 26 trimmed existing stakes and 26 added.
The largest buyer was ADAR1 Capital Management, adding an estimated $3.17M. The largest seller was Redmile Group, cutting an estimated $1.07M.
- 91 institutional investors held Pliant Therapeutics (PLRX) as of Q1 2026, down from 96 in Q4 2025.
- Funds reported $62.5M of Pliant Therapeutics stock for Q1 2026, up 8.6% quarter-over-quarter.
- 15 funds opened new Pliant Therapeutics positions in Q1 2026 and 16 closed out, a net change of -1 holder.
- The largest Pliant Therapeutics buyer in Q1 2026 was ADAR1 Capital Management, an estimated $3.17M added.
- The largest Pliant Therapeutics seller in Q1 2026 was Redmile Group, an estimated $1.07M sold.
Based on aggregated 13F filings for Q1 2026.