Renaissance Technologies
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Renaissance Technologies’s Pliant Therapeutics PLRX Stock Holding History

Renaissance Technologies’s Portfolio PLRX Stock Details PLRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.33M Buy
1,852,842
+807,024
+77% +$1.02M ﹤0.01% 1819
2025
Q4 		$1.28M Buy
1,045,818
+34,016
+3% +$51.1K ﹤0.01% 2143
2025
Q3 		$1.5M Buy
1,011,802
+811,854
+406% +$1.24M ﹤0.01% 2260
2025
Q2 		$232K Buy
199,948
+47,448
+31% +$67K ﹤0.01% 3130
2025
Q1 		$206K Buy
152,500
+124,700
+449% +$757K ﹤0.01% 3069
2024
Q4 		$366K Sell
27,800
-73,400
-73% -$1M ﹤0.01% 2975
2024
Q3 		$1.13M Sell
101,200
-152,169
-60% -$1.9M ﹤0.01% 2363
2024
Q2 		$2.72M Buy
253,369
+177,469
+234% +$2.29M ﹤0.01% 1682
2024
Q1 		$1.13M Buy
+75,900
New +$1.25M ﹤0.01% 2411
2023
Q2 		– Sell
-138,200
Closed -$3.68M – 4193
2023
Q1 		$3.68M Buy
138,200
+117,400
+564% +$3.34M ﹤0.01% 1657
2022
Q4 		$402K Sell
20,800
-73,500
-78% -$1.54M ﹤0.01% 3073
2022
Q3 		$1.97M Sell
94,300
-10,800
-10% -$207K ﹤0.01% 2019
2022
Q2 		$842K Sell
105,100
-500
-0.5% -$3.2K ﹤0.01% 2824
2022
Q1 		$740K Buy
105,600
+75,293
+248% +$768K ﹤0.01% 2927
2021
Q4 		$409K Buy
30,307
+307
+1% +$4.88K ﹤0.01% 3178
2021
Q3 		$506K Buy
+30,000
New +$637K ﹤0.01% 2886

Other funds holding PLRX

TCM
Tang Capital Management San Diego, California $1.97B AUM 125.1% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
BOCH
Blue Owl Capital Holdings New York $372M AUM 78.25% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return
MAM
Monaco Asset Management Monaco $542M AUM 54.4% 1-Year Est. Return
PM
Prosight Management Dallas, Texas $610M AUM 40.86% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return

Renaissance Technologies's PLRX Position: Q1 2026 in Review

Renaissance Technologies increased its Pliant Therapeutics (PLRX) stake by 77% in Q1 2026, buying an estimated $1.02M and bringing the position to 1,852,842 shares worth $2.33M. The position accounts for ﹤0.01% of the portfolio, ranked #1819.

Renaissance Technologies first reported a position in PLRX in Q3 2021 and has held it in 16 quarters since. The position peaked at $3.68M in Q1 2023. 91 funds tracked by Wall St. Rank hold PLRX as of Q1 2026.

  • Renaissance Technologies held 1,852,842 shares of Pliant Therapeutics worth $2.33M as of Q1 2026.
  • Renaissance Technologies bought 807,024 Pliant Therapeutics shares in Q1 2026, an estimated $1.02M.
  • Pliant Therapeutics made up ﹤0.01% of Renaissance Technologies's portfolio in Q1 2026, its #1819 holding.
  • Renaissance Technologies first reported a position in Pliant Therapeutics in Q3 2021 and has held it in 16 quarters since.
  • Renaissance Technologies's Pliant Therapeutics position peaked at $3.68M in Q1 2023.
  • 91 funds tracked by Wall St. Rank held Pliant Therapeutics as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.