Two Sigma Advisers
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Two Sigma Advisers’s Pliant Therapeutics PLRX Stock Holding History

Two Sigma Advisers’s Portfolio PLRX Stock Details PLRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-1,245,600
Closed -$1.52M – 1585
2025
Q4 		$1.52M Buy
1,245,600
+173,100
+16% +$260K ﹤0.01% 1292
2025
Q3 		$1.59M Buy
1,072,500
+617,300
+136% +$942K ﹤0.01% 1240
2025
Q2 		$528K Buy
455,200
+113,000
+33% +$160K ﹤0.01% 1725
2025
Q1 		$462K Buy
342,200
+206,500
+152% +$1.25M ﹤0.01% 1815
2024
Q4 		$1.79M Sell
135,700
-22,100
-14% -$302K ﹤0.01% 1170
2024
Q3 		$1.77M Sell
157,800
-31,900
-17% -$399K ﹤0.01% 1137
2024
Q2 		$2.04M Buy
189,700
+40,200
+27% +$518K ﹤0.01% 1181
2024
Q1 		$2.23M Buy
149,500
+56,900
+61% +$939K 0.01% 1165
2023
Q4 		$1.68M Sell
92,600
-68,800
-43% -$1.05M ﹤0.01% 1386
2023
Q3 		$2.8M Sell
161,400
-34,100
-17% -$591K 0.01% 1016
2023
Q2 		$3.54M Sell
195,500
-72,800
-27% -$1.72M 0.01% 919
2023
Q1 		$7.14M Buy
268,300
+91,100
+51% +$2.59M 0.02% 666
2022
Q4 		$3.43M Buy
177,200
+76,600
+76% +$1.6M 0.01% 947
2022
Q3 		$2.1M Buy
100,600
+45,400
+82% +$869K 0.01% 1149
2022
Q2 		$442K Sell
55,200
-21,900
-28% -$140K ﹤0.01% 1977
2022
Q1 		$540K Buy
77,100
+31,700
+70% +$323K ﹤0.01% 1952
2021
Q4 		$613K Buy
+45,400
New +$722K ﹤0.01% 1816

Other funds holding PLRX

TCM
Tang Capital Management San Diego, California $2.2B AUM 156.35% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $875B AUM 40.91% 1-Year Est. Return
BOCH
Blue Owl Capital Holdings New York $665M AUM 95.48% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $2.19B AUM 374.99% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $84.2B AUM 55.88% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
MAM
Monaco Asset Management Monaco $1.26B AUM 60.23% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return
PM
Prosight Management Dallas, Texas $580M AUM 29.81% 1-Year Est. Return

Two Sigma Advisers's PLRX Position: Q1 2026 in Review

Two Sigma Advisers sold out of Pliant Therapeutics (PLRX) in Q1 2026, closing a stake of 1,245,600 shares — an estimated $1.52M sold.

Two Sigma Advisers first reported a position in PLRX in Q4 2021 and held it in 17 quarters. The position peaked at $7.14M in Q1 2023. 91 funds tracked by Wall St. Rank hold PLRX as of Q1 2026.

  • Two Sigma Advisers reported no remaining Pliant Therapeutics position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Advisers sold 1,245,600 Pliant Therapeutics shares in Q1 2026, an estimated $1.52M.
  • Two Sigma Advisers first reported a position in Pliant Therapeutics in Q4 2021 and held it in 17 quarters.
  • Two Sigma Advisers's Pliant Therapeutics position peaked at $7.14M in Q1 2023.
  • 91 funds tracked by Wall St. Rank held Pliant Therapeutics as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.