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Karyopharm Therapeutics
KPTI

Name Holding Trade Value Shares
Change 		Change in
Stake
CC
1
Commodore Capital
New York
$10.9M +$14.9M +1,950,000 New
RCM
2
RA Capital Management
Massachusetts
$10.7M +$14.6M +1,917,354 New
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$10.1M +$10.6M +1,385,000 +329%
T. Rowe Price Investment Management
4
T. Rowe Price Investment Management
Maryland
$8.59M +$386K +50,681 +3%
Goldman Sachs
5
Goldman Sachs
New York
$5.28M +$7.22M +947,579 New
CCM
6
Catalio Capital Management
New York
$5M +$5.75M +754,725 +528%
Vanguard Capital Management
7
Vanguard Capital Management
Pennsylvania
$4.12M +$5.64M +739,745 New
IC
8
Ikarian Capital
Texas
$4.09M +$1.44M +188,881 +35%
AAA
9
Affinity Asset Advisors
New York
$2.79M -$2.97M -389,575 -44%
APM
10
Avidity Partners Management
Texas
$2.58M +$2.51M +329,175 +245%
SCM
11
Soleus Capital Management
Connecticut
$2.45M – – –
Millennium Management
12
Millennium Management
New York
$2.34M +$3.21M +420,571 New
BCM
13
Boxer Capital Management
California
$1.69M +$381K +50,000 +20%
DKCM
14
Davidson Kempner Capital Management
New York
$1.67M -$76.4K -10,020 -3%
ACA
15
Acorn Capital Advisors
New York
$1.6M +$2.19M +287,826 New
EP
16
Eversept Partners
New York
$1.54M +$2.11M +276,174 New
JF
17
Jump Financial
Illinois
$1.46M +$1.59M +208,330 +387%
TI
18
Trexquant Investment
Connecticut
$1.44M +$1.65M +216,170 +518%
Acadian Asset Management
19
Acadian Asset Management
Massachusetts
$1.38M +$1.87M +245,231 +6,582%
BlackRock
20
BlackRock
New York
$1.36M -$20.3K -2,659 -1%
BFM
21
Boothbay Fund Management
New York
$1.19M +$527K +69,182 +48%
BHCM
22
Brevan Howard Capital Management
Jersey
$1.18M +$1.62M +212,367 New
Geode Capital Management
23
Geode Capital Management
Massachusetts
$1.15M +$140K +18,399 +10%
UBS Group
24
UBS Group
Switzerland
$1.08M +$805K +105,562 +119%
Group One Trading
25
Group One Trading
Illinois
$1.07M +$679K +89,108 +87%
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