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Karyopharm Therapeutics
KPTI

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$53.8M +$43.2M +156,400 New
FCMI
2
Foresite Capital Management I
California
$32.6M +$29.2M +105,716 New
PHS
3
PFM Health Sciences
California
$19.8M +$16.4M +59,301 New
Franklin Resources
4
Franklin Resources
California
$18M +$14.5M +52,460 New
Wellington Management Group
5
Wellington Management Group
Massachusetts
$11.6M +$9.3M +33,681 New
AllianceBernstein
6
AllianceBernstein
Tennessee
$10.4M +$8.37M +30,295 New
BA
7
BlackRock Advisors
Delaware
$7.49M +$6.02M +21,788 New
TG
8
TCW Group
California
$5.53M +$4.44M +16,082 New
BFA
9
BlackRock Fund Advisors
California
$4.89M +$3.93M +14,214 New
BIT
10
BlackRock Institutional Trust
California
$2.83M +$2.28M +8,244 New
Morgan Stanley
11
Morgan Stanley
New York
$2.74M +$2.2M +7,965 New
Principal Financial Group
12
Principal Financial Group
Iowa
$2.54M +$2.04M +7,400 New
State Street
13
State Street
Massachusetts
$2.51M +$2.01M +7,288 New
JP Morgan Chase
14
JP Morgan Chase
New York
$2.49M +$2M +7,239 New
Northern Trust
15
Northern Trust
Illinois
$2.43M +$1.95M +7,064 New
CAM
16
Cormorant Asset Management
Massachusetts
$2.29M +$1.84M +6,667 New
DCM
17
Driehaus Capital Management
Illinois
$2.07M +$1.66M +6,014 New
BG
18
BlackRock Group
United Kingdom
$1.91M +$1.54M +5,560 New
Vanguard Group
19
Vanguard Group
Pennsylvania
$1.79M +$1.44M +5,222 New
Alyeska Investment Group
20
Alyeska Investment Group
Illinois
$1.72M +$1.38M +5,000 New
BBA
21
Baker Bros. Advisors
New York
$1.41M +$1.13M +4,089 New
UBS AM
22
UBS AM
Illinois
$1.07M +$862K +3,120 New
EIM
23
Essex Investment Management
Massachusetts
$890K +$715K +2,587 New
FM
24
Forward Management
California
$822K +$945K +3,422 New
Geode Capital Management
25
Geode Capital Management
Massachusetts
$812K +$653K +2,364 New
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