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Karyopharm Therapeutics
KPTI

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$71M +$45.7K +211 +0.1%
Franklin Resources
2
Franklin Resources
California
$68.5M -$6.43M -29,717 -8%
PAI
3
Palo Alto Investors
California
$41.2M +$388K +1,794 +0.9%
Millennium Management
4
Millennium Management
New York
$17.1M +$3.88M +17,908 +26%
BFA
5
BlackRock Fund Advisors
California
$13.8M -$1.1M -5,058 -7%
Vanguard Group
6
Vanguard Group
Pennsylvania
$9.3M +$54.8K +253 +0.5%
BIT
7
BlackRock Institutional Trust
California
$6.89M +$144K +666 +2%
TCM
8
Tekla Capital Management
Massachusetts
$6.63M -$6.04M -27,903 -46%
State Street
9
State Street
Massachusetts
$4.52M +$507K +2,342 +11%
Northern Trust
10
Northern Trust
Illinois
$3.31M +$121K +560 +3%
JP Morgan Chase
11
JP Morgan Chase
New York
$2.88M +$1.97M +9,119 +170%
BBA
12
Baker Bros. Advisors
New York
$2.88M – – –
CS
13
Candriam SCA
Luxembourg
$2.53M +$433K +2,000 +19%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$2.3M +$49.6K +229 +2%
FLAM
15
First Light Asset Management
Minnesota
$2.02M -$28.1K -130 -1%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$1.84M +$34.2K +158 +2%
Wells Fargo
17
Wells Fargo
California
$1.79M +$1.79M +8,263 +1,133%
GC
18
Guggenheim Capital
Illinois
$1.53M -$250K -1,156 -13%
SIP
19
Stoneridge Investment Partners
Pennsylvania
$1.42M +$30.7K +142 +2%
Bank of New York Mellon
20
Bank of New York Mellon
New York
$1.38M -$3.03K -14 -0.2%
Deutsche Bank
21
Deutsche Bank
Germany
$1.38M +$246K +1,138 +20%
MOACM
22
Mutual of America Capital Management
New York
$1.17M +$478K +2,209 +60%
New York State Common Retirement Fund
23
New York State Common Retirement Fund
New York
$1.08M – – –
BIM
24
BlackRock Investment Management
Delaware
$1.06M +$9.53K +44 +0.8%
ARTA
25
A.R.T. Advisors
New York
$1.02M -$854K -3,944 -43%
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