|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$146M
|
+$5.04M
|
+11,654
|
+3%
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
$128M
|
-$4.07M
|
-9,411
|
-3%
|
|
|
3
|
Palo Alto Investors
Palo Alto,
California
|
$47.1M
|
+$22.5M
|
+52,033
|
+82%
|
|
|
4
|
State Street
Boston,
Massachusetts
|
$33.6M
|
+$7.12M
|
+16,464
|
+25%
|
|
|
5
|
BlackRock Fund Advisors
San Francisco,
California
|
$29M
|
+$5.62M
|
+13,005
|
+22%
|
|
|
6
|
PFM Health Sciences
San Francisco,
California
|
$22.4M
|
-$8.72M
|
-20,164
|
-27%
|
|
|
7
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$19.4M
|
+$164K
|
+380
|
+0.8%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$19.1M
|
+$4M
|
+9,244
|
+25%
|
|
|
9
|
AllianceBernstein
Nashville,
Tennessee
|
$15.9M
|
+$5.02M
|
+11,622
|
+43%
|
|
|
10
|
Tekla Capital Management
Boston,
Massachusetts
|
$13M
|
–
|
–
|
–
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$12.6M
|
+$1.11M
|
+2,568
|
+9%
|
|
|
12
|
Citadel Advisors
Miami,
Florida
|
$12.3M
|
+$12.3M
|
+28,519
|
+1,680%
|
|
|
13
|
Millennium Management
New York
|
$9.92M
|
+$7.73M
|
+17,889
|
+279%
|
|
|
14
|
Cormorant Asset Management
Boston,
Massachusetts
|
$8.19M
|
–
|
–
|
–
|
|
|
15
|
BlackRock Advisors
Wilmington,
Delaware
|
$7.71M
|
+$134K
|
+310
|
+2%
|
|
|
16
|
Baker Bros. Advisors
New York
|
$5.9M
|
–
|
–
|
–
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$4.73M
|
+$82.6K
|
+191
|
+2%
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$4.34M
|
-$475K
|
-1,099
|
-9%
|
|
|
19
|
Ascend Capital
Orinda,
California
|
$4.08M
|
+$4.32M
|
+9,984
|
New
|
|
|
20
|
Guggenheim Capital
Chicago,
Illinois
|
$3.77M
|
+$229K
|
+530
|
+6%
|
|
|
21
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$3.62M
|
-$3.92M
|
-9,066
|
-51%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$3.59M
|
+$257K
|
+594
|
+7%
|
|
|
23
|
New Leaf Venture Partners
New York
|
$3.45M
|
–
|
–
|
–
|
|
|
24
|
Bank of America
Charlotte,
North Carolina
|
$3.41M
|
-$675K
|
-1,562
|
-16%
|
|
|
25
|
Bank of New York Mellon
New York
|
$3.08M
|
+$927K
|
+2,144
|
+40%
|
|
