Disc Medicine
IRON
157 hedge funds and large institutions have $1.65B invested in Disc Medicine in 2025 Q1 according to their latest regulatory filings, with 26 funds opening new positions, 75 increasing their positions, 31 reducing their positions, and 21 closing their positions.
381% more call options, than puts
Call options by funds: $1.6M | Put options by funds: $333K
142% more repeat investments, than reductions
Existing positions increased: 75 | Existing positions reduced: 31
24% more first-time investments, than exits
New positions opened: 26 | Existing positions closed: 21
6.6% more ownership
Funds ownership: 89.3% → 95.9% (+6.6%)
3% more funds holding
Funds holding: 152 → 157 (+5)
0% more funds holding in top 10
Funds holding in top 10: 8 → 8 (0)
2% less capital invested
Capital invested by funds: $1.68B → $1.65B (-$34.9M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
+$87.7M |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
+$75.5M |
| 3 |
SL
Siren LLC
Greenwich,
Connecticut
|
+$59.6M |
| 4 |
Wellington Management Group
Boston,
Massachusetts
|
+$52.7M |
| 5 |
JP Morgan Chase
New York
|
+$38.8M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Citadel Advisors
Miami,
Florida
|
-$29.4M |
| 2 |
MB
MPM BioImpact
Boston,
Massachusetts
|
-$22M |
| 3 |
O
OrbiMed
New York
|
-$20.6M |
| 4 |
PBA
Paradigm Biocapital Advisors
New York
|
-$15.9M |
| 5 |
CCM
Catalio Capital Management
New York
|
-$11.4M |
IRON Hedge Fund Activity: Q1 2025 in Review
157 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q1 2025, worth a combined $1.65B — down 2.1% from $1.68B a quarter earlier.
Buyers outnumbered sellers: 26 funds opened new IRON positions and 21 closed out — a net gain of 5 holders — while 75 added to existing stakes and 31 trimmed.
The largest buyer was RA Capital Management, opening a new position worth an estimated $87.7M. The largest seller was Citadel Advisors, cutting an estimated $29.4M.
- 157 institutional investors held Disc Medicine (IRON) as of Q1 2025, up from 152 in Q4 2024.
- Funds reported $1.65B of Disc Medicine stock for Q1 2025, down 2.1% quarter-over-quarter.
- 26 funds opened new Disc Medicine positions in Q1 2025 and 21 closed out, a net change of +5 holders.
- The largest Disc Medicine buyer in Q1 2025 was RA Capital Management, an estimated $87.7M added.
- The largest Disc Medicine seller in Q1 2025 was Citadel Advisors, an estimated $29.4M sold.
Based on aggregated 13F filings for Q1 2025.