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Disc Medicine

168 hedge funds and large institutions have $2.26B invested in Disc Medicine in 2025 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 61 increasing their positions, 45 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

254% more call options, than puts

Call options by funds: $3.08M | Put options by funds: $871K

189% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 9

36% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 45

25% more capital invested

Capital invested by funds: $1.8B → $2.26B (+$454M)

11% more funds holding

Funds holding: 151168 (+17)

0.06% more ownership

Funds ownership: 98.37%98.43% (+0.06%)

22% less funds holding in top 10

Funds holding in top 10: 97 (-2)

Holders
168
Holders Change
+17
Holders Change %
+11.26%
% of All Funds
2.2%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.09%
New
26
Increased
61
Reduced
45
Closed
9
Calls
$3.08M
Puts
$871K
Net Calls
+$2.21M
Net Calls Change
-$20.1M
Name Holding Trade Value Shares
Change
Change in
Stake
SO
126
STRS Ohio
Ohio
$145K
VIA
127
Virtus Investment Advisers
Connecticut
$143K +$22.2K +374 +21%
AIP
128
Ameritas Investment Partners
Nebraska
$128K -$34.7K -584 -23%
AF
129
Avanza Fonder
Sweden
$110K +$34.8K +585 +54%
Mirae Asset Global Investments
130
Mirae Asset Global Investments
South Korea
$88.8K +$357 +6 +0.4%
US Bancorp
131
US Bancorp
Minnesota
$77.7K -$178 -3 -0.3%
TRCT
132
Tower Research Capital (TRC)
New York
$73K -$171K -2,870 -72%
Carson Wealth (CWM LLC)
133
Carson Wealth (CWM LLC)
Nebraska
$68K -$1.01K -17 -2%
AB
134
Amalgamated Bank
New York
$52K
Simplex Trading
135
Simplex Trading
Illinois
$52K +$35.8K +601 +302%
GFM
136
GF Fund Management
China
$49.4K -$833 -14 -2%
Public Employees Retirement Association of Colorado
137
Public Employees Retirement Association of Colorado
Colorado
$48K
ACM
138
Aster Capital Management
United Arab Emirates
$38.1K +$34.3K +576 New
SPIA
139
Steward Partners Investment Advisory
New York
$35.2K
A
140
AlphaQuest
New York
$21.6K
Nisa Investment Advisors
141
Nisa Investment Advisors
Missouri
$19.4K +$535 +9 +3%
GI
142
GAMMA Investing
California
$18.2K +$2.14K +36 +15%
Osaic Holdings
143
Osaic Holdings
Arizona
$17.8K
BNP Paribas Asset Management
144
BNP Paribas Asset Management
France
$14K +$654 +11 +5%
AAP
145
Arax Advisory Partners
Colorado
$13.6K +$12.3K +206 New
Optiver Holding
146
Optiver Holding
Netherlands
$12.8K +$11.5K +194 New
LFG
147
Larson Financial Group
Missouri
$7.14K -$59 -1 -0.9%
Daiwa Securities Group
148
Daiwa Securities Group
Japan
$7K
CA
149
Clearstead Advisors
Ohio
$6.74K -$2.74K -46 -31%
EWA
150
EverSource Wealth Advisors
Alabama
$4.96K +$178 +3 +4%

IRON Hedge Fund Activity: Q3 2025 in Review

168 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Disc Medicine (IRON) for Q3 2025, worth a combined $2.26B — up 25% from $1.8B a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new IRON positions and 9 closed out — a net gain of 17 holders — while 61 added to existing stakes and 45 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $101M. The largest seller was Janus Henderson Group, cutting an estimated $70.9M.

  • 168 institutional investors held Disc Medicine (IRON) as of Q3 2025, up from 151 in Q2 2025.
  • Funds reported $2.26B of Disc Medicine stock for Q3 2025, up 25% quarter-over-quarter.
  • 26 funds opened new Disc Medicine positions in Q3 2025 and 9 closed out, a net change of +17 holders.
  • The largest Disc Medicine buyer in Q3 2025 was Fidelity Investments, an estimated $101M added.
  • The largest Disc Medicine seller in Q3 2025 was Janus Henderson Group, an estimated $70.9M sold.

Based on aggregated 13F filings for Q3 2025.